Effects of different drying methods including 40℃,60 ℃ and 80 ℃ hot air-drying and freeze-drying on the content of nutrient and physical properties of Cordyceps militaris fruiting bodies were studied.In conclusion,low temperature drying method is good for SOD enzyme activity,SOD enzyme activity in C.milita by lyophilization was 36.73U/mg;high temperature (80℃) or long time (24h) drying process were not favorite to preserve cordycepin.Cordycepin content was 148.84 μg/g by 60℃ drying and 143.14μg/g by freeze-drying for 24 hours.High temperature and short time was better for higher adenosine content.Adenosine content was 592.01μg/g at 80℃ drying for 6 hours.Four drying methods had no obvious effect on swelling properties of super micro-milling powder.Lyophilization method had the lowest flow ability.