This paper mainly explores the influence of temperature, exposure time, food simulants, oxygen, and three kinds of structure (PP-B, PP-R and PP-H) on the migration of copper from nanocopper/PP composite films into food simulants. Nanocopper and modified nanocopper by (3-Aminopropyl) triethoxysilane (KH550) were mixed with PP granules, new granules containing nanocopper and modified nanocopper were added into the composite films by a film-blowing machine. The films were exposured to food simulants at 20, 40 and 70 ℃. The results showed that with the increase of exposure time and temperature, the release of copper increased. When equilibrium is reached in acidic food simulants, copper migration does not appear to be significant in the case of PP-R and PP-H compared with nanocopper/PP-B with a maximum value at 20 ℃; copper migration does not appear to be significant in the case of PP-B and PP-R compared with PP-H with a maximum value at 40 ℃; the migration of copper in PP-H is greater than PP-R, the migration of copper in the PP-B is minimum at 70 ℃.