The heavy metals of Cd, Al, Pb, Hg, Cu, Zn were analyzed in different tissues of Ostrea rivularis from South China Sea in December, 2016.Coupled plasma mass spectrometry(ICP-MS) was used in the detecting, and the effect of visceral mass on the heavy metals were discussed.Single factor pollution index and Nemero pollution index were used to evaluate the test results.The results showed that there were significant differences of heavy mental contents in Ostrea rivularis from different areas(p<0.001), and the content of heavy mental in the same sea area also showed different.The Zn, Cu and Al contents were higher than others, and the average concentrations were 255.18,49.61 and 82.55 mg/kg, respectively.The average contents Hg was 11.80 μg/kg which was the lowest.The contents of Cd, Pb, Hg, Al and Cu in eviscerated Ostrea Rivularis was lower than those of the whole, while the Zn content was higher than that of the whole Ostrea rivularis.It was found that the heavy mental contents in different tissues of Ostrea rivularis were varied, and visceral mass was the main accumulation place of heavy metals.Ostrea rivularis have not been polluted by Pb and Hg from the tested areas, while Cu and Al contents in some Ostrea rivularis were high.