Fresh-cut apples are become very popular in recently years due to its freshness, safe, nutrition and convenience. However, some problems such as browning, softening and decay may occur during their storage due to mechanical damages during cutting apples. Chemical treatments are widely used on fresh-keeping of fresh-cut apples because of its convenient operation and low cost. This paper reviewed applications of some chemical treatments on keeping the quality of fresh-cut apples, such as novel fungicides, calcium treatments, browning inhibitors, edible coatings and chemical and physical combined treatment. Probable mechanisms of inhibiting browning, enhancing slice hardness and controlling the growth and reproduction of microorganism were also analyzed and discussed. The quality of fresh-cut apples can be well kept by these techniques during storage.