Research progress on fermented milk regulating human intestinal nutrition and health

  • DING Rui-xue ,
  • WANG Yi-ran ,
  • WU Ri-na ,
  • YUE Xi-qing ,
  • LUO Xue ,
  • WU Jun-rui
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  • (College of Food Science, Shenyang Agricultural University, Shenyang 110866, China)

Received date: 2018-06-07

  Online published: 2019-01-22

Abstract

With the vast research achievements obtained in the field of intestinal flora and intestinal nutrition health, new understandings on human nutrition and health regulation are addressed. Therefore, it has become a consensus that the use of healthy diet such as fermented milk to intervene or regulate intestinal nutrition and health and thus prevent and even treat chronic diseases of the human body and the relative researches have been carried out and significant progresses have been made. Recent research progresses on the fermented milk and its main ingredients for intestinal cell nutrition metabolic regulation, regulatory mechanisms, and applications in certain disease prevention and treatment were reviewed. It provides a comprehensive reference for related research and application.

Cite this article

DING Rui-xue , WANG Yi-ran , WU Ri-na , YUE Xi-qing , LUO Xue , WU Jun-rui . Research progress on fermented milk regulating human intestinal nutrition and health[J]. Food and Fermentation Industries, 2018 , 44(12) : 281 -287 . DOI: 10.13995/j.cnki.11-1802/ts.017984

References

[1] 王文娟,孙冬岩,孙笑非,等. 肠道菌群对宿主黏膜免疫和营养代谢的关系研究进展[J]. 饲料研究, 2015(10): 28-29,39.<br /> [2] 苏海霞. 乳制品的分类与营养[J]. 食品安全导刊, 2016(25): 55-56.<br /> [3] 李玉珍. 不同传统发酵乳成分及功能特性的比较研究[D]. 呼和浩特:内蒙古农业大学, 2015.<br /> [4] 张兰威.发酵食品工艺学[M]. 北京:中国轻工业出版社, 2011:283-284.<br /> [5] 张和平. 益生乳酸菌及发酵乳的开发趋势[J]. 农产品加工, 2012(6): 8-9.<br /> [6] RODR GUEZ S, SANTAMAR A R I, FERN NDEZ-BALOS J M, et al. Identification of the sequences involved in the glucose-repressed transcription of the Streptomyces halstedii JM8 xysA promoter[J]. Gene, 2005, 351: 1-9.<br /> [7] XU Guang-yong, JIANG Jin-qi, WANG ming et al. Lactic Acid Reduces LPS-Induced TNF-α and IL-6 mRNA Levels Through Decreasing IKBα Phosphorylation[J]. Journal of Integrative Agriculture, 2013, 12(6): 1 073-1 078.<br /> [8] 崔玉琦,王雅炜,武瑞霞,等.酵母菌在发酵乳制品中的应用研究[J].食品科技,2014, 39(10):53-56.<br /> [9] 李凯年. 用苯甲酸改善肉鸡肠道菌群[J]. 中国动物保健, 2013, 15 (11):85.<br /> [10] 温永平,侯强川,张和平. 自然发酵酸马奶对人体肠道菌群的影响——基于PacBio SMRT测序技术[J]. 中国乳品工业,2017,45(2): 4-7.<br /> [11] LOUIS P, FLINT H J. Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine[J]. FEMS microbiology letters, 2009, 294(1): 1-8.<br /> [12] DESROUILLE·RES K, MILLETTE M, JAMSHIDIAN M, et al. Cancer preventive effect of a specific probiotic fermented milk components and cell walls extracted from a biomass containing <i>L. acidophilus</i> CL1285, <i>L. casei</i> LBC80R, and <i>L. rhamnosus</i> CLR2 on male F344 rats treated with 1, 2-dimethylhydrazine[J]. Journal of Functional Foods, 2016, 26: 373-384.<br /> [13] ZIMMER J, LANGE B, FRICK J S, et al. A vegan or vegetarian diet substantially alters the human colonic faecal microbiota[J]. European journal of clinical nutrition, 2012, 66(1): 53-60.<br /> [14] 李超,王春凤,杨桂连,等. 乳酸菌胞外多糖肠道黏附及免疫调节作用研究进展[J]. 食品科学,2014, 35(11):314-318.<br /> [15] GARG S, SINGH T P, REDDI S, et al. Intervention of probiotic L. reuteri fermented milk as an adjuvant to combat protein energy malnourishment induced gut disturbances in albino mice[J]. Journal of Functional Foods, 2017, 36: 467-479.<br /> [16] 陈妍婕. 乳酸杆菌在全谷物糙米乳中发酵特性的研究[D]. 锦州:渤海大学,2016.<br /> [17] 华鹤良. 乳酸菌的分离鉴定及其抗菌肽与发酵性能的研究[D]. 扬州:扬州大学,2014.<br /> [18] 药璐. 益生菌发酵乳发酵工艺优化与品质研究[D]. 长春:吉林农业大学,2013.<br /> [19] KAMAO M, TSUGAWA N, NAKAGAWA K, et al. Absorption of calcium, magnesium, phosphorus, iron and zinc in growing male rats fed diets containing either phytate-free soybean protein or soybean protein isolate or casein[J]. Journal of nutritional science and vitaminology, 2000, 46(1): 34-41.<br /> [20] 刘瑞雪,李勇超,张波.肠道菌群微生态平衡与人体健康的研究进展[J].食品工业科技,2016, 37(6): 383-387,391.<br /> [21] MATSUMOTO K, TAKADA T, SHIMIZU K, et al. Effects of a probiotic fermented milk beverage containing <i>Lactobacillus casei</i> strain Shirota on defecation frequency, intestinal microbiota, and the intestinal environment of healthy individuals with soft stools[J]. Journal of bioscience and bioengineering, 2010, 110(5): 547-552.<br /> [22] 汪志铮.酸奶的保健功能及四种特色酸奶加工技术[J]. 草业与畜牧,2014,213(2):43-45,62.<br /> [23] 李远. 新疆酸驼乳中乳酸菌分离鉴定及其细菌素研究[D]. 乌鲁木齐:新疆农业大学,2011.<br /> [24] CHANDAN R, KILARA A. Manufacturing Yogurt and fermented milks[M]. Chichester: John Wiley &Sons, Inc. 2013:394-409.<br /> [25] XUE Chao-hui, ZHANG Lan-wei, Li Hong-bo, et al. Functionality of the S-layer proteins from Lactobacillus in the competitive against enteropathogens infection[D]. European Food Research and Technology, 2013, 236(2): 249-255.<br /> [26] LINSALATA M, RUSSO F. Nutritional factors and polyamine metabolism in colorectal cancer[J]. Nutrition, 2008, 24(4): 382-389.<br /> [27] ZHANG Ying-chun, ZHANG Lan-wei, MA Wei, et al. Screening of probiotic lactobacilli for inhibition of <i>Shigella sonnei</i> and the macromolecules involved in inhibition[J]. Anaerobe, 2012, 18(5): 498-503. <br /> [28] 胡盼盼,刘新民,喻智强,等. 副干酪乳杆菌诱导Caco-2细胞凋亡及其发酵乳贮藏品质的研究[J]. 中国酿造, 2017, 36(9): 142-147.<br /> [29] MATSUMOTO M, OHISHI H, BENNO Y. Impact of LKM512 yogurt on improvement of intestinal environment of the elderly[J]. FEMS Immunology & Medical Microbiology, 2001, 31(3): 181-186.<br /> [30] GAO Jie, GU Feng-ying, RUAN Hui, et al. Induction of apoptosis of gastric cancer cells SGC7901 in vitro by a cell-free fraction of Tibetan kefir[J]. International Dairy Journal, 2013, 30(1): 14-18.<br /> [31] WANG Shi-jie, ZHU Hong, LU C Y, et al. Fermented milk supplemented with probiotics and prebiotics can effectively alter the intestinal microbiota and immunity of host animals[J]. Journal of Dairy Science, 2012, 95(9): 4 813-4 822.<br /> [32] SHENBHAGARAMAN R, PREMALATHA M K, JENEFAR S, et al. Immunopotentiating properties of extracellular polysaccharide from <i>Trametes hirsuta</i> strain VKESR[J]. Carbohydrate polymers, 2014, 106: 299-304.<br /> [33] 冀朵朵,张国亮,金苏,等. 开菲尔奶抑制肠道致病菌、降胆固醇及调节免疫功能研究[J]. 中国乳品工业,2009, 37(8):4-8.<br /> [34] IRAPORDA C, ROMANIN D E, RUMBO M, et al. The role of lactate on the immunomodulatory properties of the nonbacterial fraction of kefir[J]. Food research international, 2014, 62: 247-253.<br /> [35] BAKIR B, SARI E K, AYDIN B D, et al. Immunohistochemical examination of effects of kefir, koumiss and commercial probiotic capsules on platelet derived growth factor-c and platelet derived growth factor receptor-alpha in mouse liver and kidney[J]. Biotechnic & Histochemistry, 2015, 90(3): 190-196.<br /> [36] 姜晶. 酸马奶中植物乳酸杆菌HS-R9的分离鉴定、细菌素提取及对小鼠免疫屏障的影响[D]. 呼和浩特:内蒙古农业大学,2016.<br /> [37] 李银聪. 自然发酵酸牦牛奶的微生物区系及其抗氧化活性研究[D]. 重庆:西南大学, 2011.<br /> [38] DING Wu-rong, WANG Li-na, ZHANG Juan, et al. Characterization of antioxidant properties of lactic acid bacteria isolated from spontaneously fermented yak milk in the Tibetan Plateau[J]. Journal of Functional Foods, 2017, 35: 481-488.<br /> [39] 孟和毕力格,周雨霞,张和平. 酸马奶中乳杯菌MG2-1株的抗氧化活性作用研究[J].中国乳品工业,2005, 33(9):21-24.<br /> [40] 乌仁图雅, 哈斯苏荣,嗄力宾嗄,等.双峰驼自然发酵乳对小鼠抗氧化作用的影响[J]. 内蒙古农业大学学报,2010, 31(2):6-9<br /> [41] AYYASH M, Al-NUAIMI A K, AI-MAHADIN S, et al. In vitro investigation of anticancer and ACE-inhibiting activity, α-amylase and α-glucosidase inhibition, and antioxidant activity of camel milk fermented with camel milk probiotic: A comparative study with fermented bovine milk[J]. Food chemistry, 2018, 239: 588-597.<br /> [42] DING Wu-rong, SHI Chao, Chen Ming, et al. Screening for lactic acid bacteria in traditional fermented Tibetan yak milk and evaluating their probiotic and cholesterol-lowering potentials in rats fed a high-cholesterol diet[J]. Journal of Functional Foods, 2017, 32: 324-332.<br /> [43] 武运,王璐,阎晓菲,等. 混合菌种发酵酸马乳的降血脂功能研究[J]. 食品工业科技,2015,36(2):355-357.<br /> [44] AHMED Z, WANG Yan-ping, Ahmad A, et al. Kefir and health: a contemporary perspective[J]. Critical reviews in food science and nutrition, 2013, 53(5): 422-434.<br /> [45] 高洁,孙静,黄建,等. 开菲尔对高脂金黄地鼠肠道菌群的调节作用研究[J]. 中国酿造,2017, 36(4):15-19.<br /> [46] GUO Chun-feng, DI Zhao, YUAN Ya-hong, et al. Lactobacillus casei-fermented milk improves serum and hepatic lipid profiles in diet-induced hypercholesterolaemic hamsters[J]. Journal of Functional Foods, 2016, 26: 691-697.<br /> [47] 陈玉洁. 酸马奶源酵母菌代谢物对致病性大肠杆菌的抑菌作用机理研究[D]. 呼和浩特:内蒙古农业大学,2015.<br /> [48] 汪建紅,周克夫. 骆驼奶对Ⅱ型糖尿病防治作用试验研究[J]. 四川动物, 2013, 32(6):830-834.<br /> [49] ELAHI S, ERTELT J M, KINDER J M, et al. Immunosuppressive CD71<sup>+</sup> erythroid cells compromise neonatal host defence against infection[J]. Nature, 2013, 504(7478): 158-162.<br /> [50] 曹永强. 干酪乳杆菌N1115产酸特性及其在发酵乳中的应用[D]. 北京:北京工商大学, 2016.<br /> [51] ZUBILLAGA M, WEILL R, POSTAIRE E, et al. Effect of probiotics and functional foods and their use in different diseases[J]. Nutrition research, 2001, 21(3): 569-579.
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