In an acidic medium of pH 3.46, carbamazepine reacted with coomassie brilliant blue- cetylpyridyl bromide to form an ion association, which led to the resonance light scattering (RLS) signal increased obviously. At the maximal resonant light scattering wavelength of 344 nm, the mass concentration of carbamazepine in the range of 0.006-0.33 mg/L showed a good linear relationship with the increase in resonant light scattering intensity (ΔIRLS). The detection limit was 0.0056 mg/ L and the limit of quantitation was 0.012 mg/kg. Based on the above results, a rapid, accurate, highly sensitive new RLS method for determining carbamazepine in meat foods was established. This method was applied to determine residual carbamazepine in meat foods with 98.5%-102% recovery rate and the relative standard deviation (n=5) was 2.2%-2.6%.
JIANG Hong
,
PANG Xiangdong
,
WU Xiaoyan
,
CHENG Dan
,
LI Na
. Studies on detecting carbamazepine residues in food using high sensitive resonant light scattering technique[J]. Food and Fermentation Industries, 2019
, 45(4)
: 206
-210
.
DOI: 10.13995/j.cnki.11-1802/ts.017736
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