YUAN Shengliang , DUAN Zhihong , LU Yingnian , MA Xiaoli , OUYANG Peipei . Research progress on seaweed polyphenolic compounds and their antioxidant activities[J]. Food and Fermentation Industries, 2019 , 45(5) : 274 -281 . DOI: 10.13995/j.cnki.11-1802/ts.017701

[1] ASANKA S K K, LEE W W, KIM J I, et al. Exploiting biological activities of brown seaweed Ishige okamurae Yendo for potential industrial applications: a review[J]. Journal of Applied Phycology, 2017, 29(6): 3 109-3 119.<br /> [2] RICO M, GONZ LEZ A G, SANTANA C M, et al. Production of primary and secondary metabolites using algae[J]. Prospects and Challenges in Algal Biotechnology, 2017:311-326.<br /> [3] WANG H D, LI X C, LEE D J, et al. Potential biomedical applications of marine algae[J]. Bioresour Technol, 2017, 244(2): 1 407-1 415.<br /> [4] MASISI K, BETA T, MOGHADASIAN M H. Antioxidant properties of diverse cereal grains: A review on <i>in vitro</i> and in vivo studies[J]. Food Chem, 2016, 196:90-97.<br /> [5] 丁兰平,黄冰心,谢艳齐. 中国大型海藻的研究现状及其存在的问题[J]. 生物多样性, 2011, 19(6): 798-804.<br /> [6] FERNADO I P S, KIM M, SON K T, et al. Antioxidant activity of marine algal polyphenolic compounds: A mechanistic approach[J]. Journal of Medicinal Food, 2016, 19(7): 615-628.<br /> [7] RAMCHOUN M, HARNAFI H, ALEM C, et al. Hypolipidemic and antioxidant effect of polyphenol-rich extracts from <i>Moroccanthyme varieties</i>[J]. e-SPEN Journal, 2012, 7(3): e119-e124.<br /> [8] SERRA A T, DUARTE R O, BRONZE M R, et al. Identification of bioactive response in traditional cherries from Portugal[J]. Food Chemistry, 2011, 125(2): 318-325.<br /> [9] ABDUL Q A, CHOI R J, JUNG H A, et al. Health benefit of fucosterol from marine algae: a review[J]. Journal of the Science of Food and Agriculture, 2016, 96(6): 1 856-1 866.<br /> [10] 李冰心,李颖畅,励建荣. 海藻多酚的提取及其生物活性研究进展[J]. 食品与发酵科技, 2012, 48(5): 12-15.<br /> [11] TSAO R. Chemistry and biochemistry of dietary polyphenols[J]. Nutrients, 2010, 2(12): 1 231-1 246.<br /> [12] 彭雍博,罗宣,汪秋宽,等. 海藻多酚功能性作用机制及其应用研究[J]. 大连海洋大学学报, 2017, 32(4): 484-492.<br /> [13] LI Y X, WIJESEKARA I, LI Y, et al. Phlorotannins as bioactive agents from brown algae[J]. Process Biochemistry, 2011, 46(12): 2 219-2 224.<br /> [14] LI Yong, QIAN Zhongji, RYU B, et al. Chemical components and its antioxidant properties <i>in vitro</i>: an edible marine brown alga, <i>Ecklonia cava</i>[J]. Bioorganic & Medicinal Chemistry, 2009, 17(5): 1 963-1 973.<br /> [15] KIM S Y, KIM E A, KANG M C, et al. Polyphenol-rich fraction from <i>Ecklonia cava</i> (a brown alga) processing by-product reduces LPS-induced inflammation <i>in vitro</i> and <i>in vivo</i> in a zebrafish model[J]. Algae, 2014, 29(2): 165-174.<br /> [16] MWANGI H M, VAN D W J, MARNEWICK J, et al. Isolation, identification and radical scavenging activity of phlorotannin derivatives from brown algae, <i>Ecklonia maxima</i>: An experimental and theoretical study[J]. Free Radicals and Antioxidants, 2013, 3(Suppl):S1-S10.<br /> [17] JUNG H A, KIM J I, CHOUNG S Y, et al. Protective effect of the edible brown alga <i>Ecklonia stolonifera</i> on doxorubicin-induced hepatotoxicity in primary rat hepatocytes[J]. The Journal of Pharmacy and Pharmacology, 2014, 66(8): 1 180-1 188.<br /> [18] CORONA G, JI Y, ANEGBOONLAP P, et al. Gastrointestinal modifications and bioavailability of brown seaweed phlorotannins and effects on inflammatory markers[J]. The British Journal of Nutrition, 2016, 115(7): 1 240-1 253.<br /> [19] KIM H H, KIM H S, KO J Y, et al. A single-step isolation of useful antioxidant compounds from <i>Ishige okamurae</i> by using centrifugal partition chromatography[J]. Fisheries and Aquatic Sciences, 2016, 19(1): 22-29.<br /> [20] RAJAURIA G, FOLEY B, ABU G N. Identification and characterization of phenolic antioxidant compounds from brown Irish seaweed <i>Himanthalia elongata</i> using LC-DAD-ESI-MS/MS[J]. Innovative Food Science & Emerging Technologies, 2016, 37(Part B):261-268.<br /> [21] KLEJDUS B, LOJKOVA L, PLAZA M, et al. Hyphenated technique for the extraction and determination of isoflavones in algae: ultrasound-assisted supercritical fluid extraction followed by fast chromatography with tandem mass spectrometry[J]. Journal of Chromatography. A, 2010, 1 217(51): 7 956-7 965.<br /> [22] AGREGAN R, MUNEKATA P E S, FRANCO D, et al. Phenolic compounds from three brown seaweed species using LC-DAD-ESI-MS/MS[J]. Food Research International, 2017, 99(Pt 3): 979-985.<br /> [23] MACHU L, MISURCOVA L, AMBROZOVA J V, et al. Phenolic content and antioxidant capacity in algal food products[J]. Molecules, 2015, 20(1): 1 118-1 133.<br /> [24] ONOFREJOVA L, VASICKOVA J, KLEJDUS B, et al. Bioactive phenols in algae: the application of pressurized-liquid and solid-phase extraction techniques[J]. Journal of Pharmaceutical and Biomedical Analysis, 2010, 51(2): 464-470.<br /> [25] MEZGHANI S, CSUPOR D, BOURGUIBA I, et al. Characterization of phenolic compounds of ulva rigida (Chlorophycae) and its antioxidant activity[J]. European Journal of Medicinal Plants, 2016, 12(1): 1-9.<br /> [26] CHAKRABORTY K, JOSEPH D. Antioxidant potential and phenolic compounds of brown seaweeds <i>Turbinaria conoides</i> and <i>Turbinaria ornata</i> (Class: Phaeophyceae)[J]. Journal of Aquatic Food Product Technology, 2016, 25(8): 1 249-1 265.<br /> [27] LI Ke, LI Xiao-ming, JI Nai-yun, et al. Bromophenols from the marine red alga polysiphonia urceolata with DPPH radical scavenging activity[J]. Journal of Natural Products, 2008, 71(1):28-30.<br /> [28] LI Ke, LI Xiao-ming, GLOER J B, et al. New nitrogen-containing bromophenols from the marine red alga <i>Rhodomela confervoides</i> and their radical scavenging activity[J]. Food Chemistry, 2012, 135(3): 868-872.<br /> [29] KIM S Y, KIM S R, OH M J, et al. <i>In vitro</i> antiviral activity of red alga, <i>Polysiphonia morrowii</i> extract and its bromophenols against fish pathogenic infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus[J]. Journal of Microbiology, 2011, 49(1): 102-106.<br /> [30] LEE J C, HOU M F, HUANG H W, et al. Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties[J]. Cancer Cell International, 2013, 13(55): 123-131.<br /> [31] CHANG M Y, BYON S H, SHIN H C, et al. Protective effects of the seaweed phlorotannin polyphenolic compound dieckol on gentamicin-induced damage in auditory hair cells[J]. International Journal of Pediatric Otorhinolaryngology, 2016, 83:31-36.<br /> [32] KIM A R, SHIN T S, LEE M S, et al. Isolation and identification of phlorotannins from <i>Ecklonia stolonifera</i> with antioxidant and anti-inflammatory properties[J]. Journal of Agricultural and Food Chemistry, 2009, 57(9): 3 483-3 489.<br /> [33] SEYOUM A, ASRES K, EL-FIKY F K. Structure-radical scavenging activity relationships of flavonoids[J]. Phytochemistry, 2006, 67(18): 2 058-2 070.<br /> [34] LA B S, POTIN P, LEBLANC C, et al. The halogenated metabolism of brown algae (Phaeophyta), its biological importance and its environmental significance[J]. Marine Drugs, 2010, 8(4): 988-1 010.<br /> [35] PIAO M J, KANG K A, RYU Y S, et al. The red algae compound 3-bromo-4,5-dihydroxybenzaldehyde protects human keratinocytes on oxidative stress-related molecules and pathways activated by UVB irradiation[J]. Marine Drugs, 2017, 15(9): 268-280.<br /> [36] LIU Ming, HANSEN P E, LIN Xiu-kun. Bromophenols in marine algae and their bioactivities[J]. Marine Drugs, 2011, 9(7): 1 273-1 292.<br /> [37] LEE J H, LEE T K, KANG R S, et al. The in vitro antioxidant activities of the bromophenols from the red alga <i>Tichocarpus crinitus</i> and phenolic derivatives[J]. Journal of the Korean Magnetic Resonance Society 2007, 11:56-63.<br /> [38] LOPEZ T C, ROCA M, GARCIA V A, et al. Oxidative stress and antioxidant status in patients with late-onset gestational diabetes mellitus[J]. Acta Diabetologica, 2013, 50(2): 201-208.<br /> [39] BALBOA E M, CONDE E, MOURE A, et al. <i>In vitro</i> antioxidant properties of crude extracts and compounds from brown algae[J]. Food Chemistry, 2013, 138:1 764-1 785.<br /> [40] COLLINS K G, FITZGERALD G F, STANTON C, et al. looking beyond the terrestrial: the potential of seaweed derived bioactives to treat non-communicable diseases[J]. Marine Drugs, 2016, 14(3): 270-281.<br /> [41] QUIDEAU S, DEFFIEUX D, DOUAT C C, et al. Plant polyphenols: chemical properties, biological activities, and synthesis[J]. Angewandte Chemie, 2011, 50(3): 586-621.<br /> [42] KOZLOWSKI D, TROUILLAS P, CALLISTE C, et al. Density functional theory study of the conformational, electronic, and antioxidant properties of natural chalcones[J]. Journal of Physical Chemistry A,2007, 111:1 138-1 145.<br /> [43] TROUILLAS P, MARSAL P, SVOBODOVA A, et al. Mechanism of the antioxidant action of silybin and 2,3-dehydrosilybin flavonolignans: A joint experimental and theoretical study[J]. Journal of Physical Chemistry A, 2008, 112:1 054-1 063.<br /> [44] 符莎露,吴甜甜,吴春华,等. 植物多酚的抗氧化和抗菌机理及其在食品中的应用[J]. 食品工业, 2016, 37(6): 242-246.<br /> [45] CERANTOLA S, BRETON F, AR G E, et al. Co-occurrence and antioxidant activities of fucol and fucophlorethol classes of polymeric phenols in <i>Fucus spiralis</i>[J]. Botanica Marina, 2006, 49(4): 347-351.<br /> [46] HERMUND D B, PLAZA M, TURNER C, et al. Structure dependent antioxidant capacity of phlorotannins from Icelandic fucus vesiculosus by UHPLC-DAD-ECD-QTOFMS[J]. Food Chemistry, 2018, 240:904-909.<br /> [47] 杨小青,卢虹玉,李延平,等. 羊栖菜不同分子质量褐藻多酚抗氧化活性研究[J]. 海洋科学, 2013, 37(4): 47-51.<br /> [48] KINDLEYSIDES S, QUEK S Y, MILLER M R. Inhibition of fish oil oxidation and the radical scavenging activity of New Zealand seaweed extracts[J]. Food Chemistry, 2012, 133(4): 1 624-1 631.<br /> [49] AIRANTHI M K, HOSOKAWA M, MIYASHITA K. Comparative antioxidant activity of edible Japanese brown seaweeds[J]. Journal of Food Science, 2011, 76(1): C104-111.<br /> [50] ZUBIA M, FABRE M S, KERJEAN V, et al. Antioxidant and antitumoural activities of some Phaeophyta from Brittany coasts[J]. Food Chemistry, 2009, 116(3): 693-701.<br /> [51] PINTEUS S, SILVA J, ALVES C, et al. Cytoprotective effect of seaweeds with high antioxidant activity from the Peniche coast (Portugal)[J]. Food Chemistry, 2017, 218:591-599.<br /> [52] LOPEZ A, RICO M, RIVERO A, et al. The effects of solvents on the phenolic contents and antioxidant activity of <i>Stypocaulon scoparium</i> algae extracts[J]. Food Chemistry, 2011, 125(3): 1 104-1 109.<br /> [53] LAMIA M. Anti-inflammatory, anti-proliferative and anti-oxidant activities of organic extracts from the Mediterranean seaweed, <i>Cystoseira crinita</i>[J]. African Journal of Biotechnology, 2011, 10(73): 16 682-16 690.<br /> [54] GONZ L L N, MOURE A, DOMINGUEZ H. Hydrothermal fractionation of <i>Sargassum muticum</i> biomass[J]. Journal of Applied Phycology, 2012, 24(6): 1 569-1 578.<br /> [55] PLAZA M, AMIGO B M, CASTILLO M D, et al. Facts about the formation of new antioxidants in natural samples after subcritical water extraction[J]. Food Research International, 2010, 43(10): 2 341-2 348.<br /> [56] STENGEL D B, CONNAN S, POPPER Z A. Algal chemodiversity and bioactivity: sources of natural variability and implications for commercial application[J]. Biotechnology Advances, 2011, 29(5): 483-501.<br /> [57] ZUBIA M, PAYRI C, DESLANDES E. Alginate, mannitol, phenolic compounds and biological activities of two range-extending brown algae, <i>Sargassum mangarevense</i> and <i>Turbinaria ornata</i> (Phaeophyta: Fucales), from Tahiti (French Polynesia)[J]. Journal of Applied Phycology, 2008, 20(6): 1 033-1 043.