Research progress and trends of electrodialysis in amino acid separation

  • XIONG Neng ,
  • CHEN Tao ,
  • SUN Zili ,
  • LIU Zhiqiang
Expand
  • 1 (Key Laboratory of Bioorganic Synthesis of Zhejiang Province (Zhejiang University of Technology), Hangzhou 310014, China)
    2 (Engineering Research Center of Bioconversion and Biopurification (Zhejiang University of Technology), Hangzhou 310014, China)
    3 (National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals (Zhejiang University of Technology), Hangzhou 310014, China)

Received date: 2019-04-16

  Online published: 2019-09-23

Abstract

Electrodialysis is an emerging technique that has recently applied in the field of amino acid separation. It has the advantages of high separation efficiency, good selectivity, simple operation and reduced water consumption, and has broad prospects for development. This paper first compares electrodialysis with other techniques in amino acid separation, points out its advantages and limitations, then analyses the influence of membrane materials and operation conditions on the separation efficiency, as well as the biggest problem that limits the development of electrodialysis: membrane fouling. Several solutions for membrane fouling are also introduced. It is found that depending on the separated amino acid, selecting the membrane with specific selectivity, as well as the matching operation conditions such as pH is crucial. A favorable product yield can therefore be achieved. The prevention and control of membrane fouling can be achieved by purifying and pretreating the feed solution, performing electrode switching and equipment cleaning, and modifying the membrane material to prepare anti-fouling membrane. In this paper, the current application of electrodialysis in amino acid separation has been reviewed. It is expected to provide theoretical support and reference for researchers in the field of amino acid separation, and accelerate the industrialization of electrodialysis in the amino acid industry.

Cite this article

XIONG Neng , CHEN Tao , SUN Zili , LIU Zhiqiang . Research progress and trends of electrodialysis in amino acid separation[J]. Food and Fermentation Industries, 2019 , 45(16) : 286 -292 . DOI: 10.13995/j.cnki.11-1802/ts.020861

References

[1] WU G Y, WU Z L, DAI Z L, et al. Dietary requirements of "nutritionally non-essential amino acids" by animals and humans[J]. Amino Acids, 2013, 44(4): 1 107-1 113.
[2] ELISSEEVA T V, SHAPOSHNIK V A, LUSCHIK I G. Demineralization and separation of amino acids by electrodialysis with ion-exchange membranes[J]. Desalination, 2002,149(1-3): 405-409.
[3] KIM S W, CHEN H Y, PARNSEN W. Regulatory role of ammo acids in pigs fed on protein-restricted diets[J]. Current Protein & Peptide Science, 2019,20(2): 132-138.
[4] 陈宁,范晓光.我国氨基酸产业现状及发展对策[J]. 发酵科技通讯, 2017,46(4): 5-9.
[5] BECKER J, ZELDER O, HAFNER S, et al. From zero to hero-design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production[J]. Metabolic Engineering, 2011,13(2): 159-168.
[6] 吴传隆,郑道敏,姚如杰,等.一种D,L-蛋氨酸的环保清洁生产方法[P]. 中国: CN106432018A, 2017-02-22.
[7] 陈佑宁,杨小玲,温晔,等.从人发中提取胱氨酸的探索[J]. 应用化工, 2007,36(6): 628-629.
[8] 周圆圆.毛发水解液中L-丝氨酸的分离及相关分析检测方法的建立[D]. 武汉:华中科技大学, 2007.
[9] CASCAVAL D, ONISCU C, GALACTION A I. Selective separation of amino acids by reactive extraction[J]. Biochemical Engineering Journal, 2001,7(3): 171-176.
[10] ZHANG Y, CHEN Y, YUE M, et al. Recovery of L-lysine from L-lysine monohydrochloride by ion substitution using ion-exchange membrane[J]. Desalination, 2011,271(1-3): 163-168.
[11] SHAPOSHNIK V A, KESORE K. An early history of electrodialysis with permselective membranes[J]. Journal of Membrane Science, 1997,136(1-2): 35-39.
[12] SUN Zhantong, GAO Xueli, ZHANG Yushan, et al. Separation and purification of L-phenylalanine from the fermentation broth by electrodialysis[J]. Desalination & Water Treatment, 2016,57(47): 1-7.
[13] WU J, XU C Q, ZHANG C Y, et al. Desalination of L-threonine (THR) fermentation broth by electrodialysis[J]. Desalination and Water Treatment, 2017,81: 47-58.
[14] STRATHMANN H. Electrodialysis, a mature technology with a multitude of new applications[J]. Desalination, 2010. 264(3): 268-288.
[15] 李爱玉,王三反,宋小三,等.离子交换膜的制备及发展趋势研究[J].环境科学与管理, 2017,42(5): 102-105.
[16] ZHOU J, ZUO P, LIU Y, et al. Ion exchange membranes from poly(2,6-dimethyl-1,4-phenylene oxide) and related applications[J]. Science China-Chemistry, 2018,61(9): 1 062-1 087.
[17] 车建业.无机离子交换在放射性废液处理中的应用[J]. 化工管理, 2016(12): 96-96.
[18] GE L, WU B, YU D, et al. Monovalent cation perm-selective membranes (MCPMs): New developments and perspectives[J]. Chinese Journal of Chemical Engineering, 2017,25(11): 1 606-1 615.
[19] WANG Y M, ZHANG Z H, JIANG C X, et al. Recovery of gamma-aminobutyric acid (GABA) from reaction mixtures containing salt by electrodialysis[J]. Separation and Purification Technology, 2016,170: 353-359.
[20] AMADO F D R, RODRIGUES L F, RODRIGUES M A S, et al. Development of polyurethane/polyaniline membranes for zinc recovery through electrodialysis[J]. Desalination,2005,186(1-3): 199-206.
[21] JIANG C X, WANG Q Y, ZHANG Y L, et al. Separation of methionine from the mixture with sodium carbonate using bipolar membrane electrodialysis[J]. Journal of Membrane Science, 2016,498: 48-56.
[22] HABE H, N YAMANO, S TAKEDA, et al. Use of electrodialysis to separate and concentrate gamma-amino butyric acid[J]. Desalination, 2010,253(1-3): 101-105.
[23] ELISEEVA T V, SHAPOSHNIK V A, KRISILOVA E, et al. Transport of basic amino acids through the ion-exchange membranes and their recovery by electrodialysis[J]. Desalination, 2009,241(1-3): 86-90.
[24] ELISEEVA T V, KRISILOVA E V, CHERNIKOV M A. Concentration of basic amino acids by electrodialysis[J]. Petroleum Chemistry, 2011,51(8): 626-633.
[25] RAN J, WU L, HE Y, et al. Ion exchange membranes: New developments and applications[J]. Journal of Membrane Science, 2017,522: 267-291.
[26] CHAI P, WANG J, LU H. The cleaner production of monosodium L-glutamate by resin-filled electro-membrane reactor[J]. Journal of Membrane Science, 2015,493: 549-556.
[27] AGHAJANYAN A E, HAMBARDZUMYAN A A, VARDANYAN A A, et al. Desalting of neutral amino acids fermentative solutions by electrodialysis with ion-exchange membranes[J]. Desalination, 2008,228(1-3): 237-244.
[28] KIKUCHI K, GOTOH T, TAKAHASHI H, et al. Separation of amino-acids by electrodialysis with ion-exchange membranes[J]. Journal of Chemical Engineering of Japan, 1995,28(1): 103-109.
[29] LIU H, RUAN H, ZHAO Y, et al. A facile avenue to modify polyelectrolyte multilayers on anion exchange membranes to enhance monovalent selectivity and durability simultaneously[J]. Journal of Membrane Science, 2017,543: 310-318.
[30] YUAN F F, WANG Q, YANG P B, et al. Influence of different resins on the amino acid recovery by resin-filling electrodialysis[J]. Separation and Purification Technology, 2015,153: 51-59.
[31] 曹刚,何绪文.电渗析膜污染的成因及控制方法研究现状[J]. 黑龙江科技信息, 2015(18): 43.
[32] JIN W Q, TOUTIANOUSH A, TIEKE B. Size-and charge-selective transport of aromatic compounds across polyelectrolyte multilayer membranes[J]. Applied Surface Science, 2005,246(4): 444-450.
[33] LE X T. Concentration polarization and conductance of cation exchange membranes in sulfuric acid and alkaline sulfate media[J]. Journal of Membrane Science, 2012,397: 66-79.
[34] REN H,WANG Q, WU X, et al. Characterization of cation-exchange membrane fouling during bipolar membrane electrodialysis of monosodium glutamate isoelectric supernatant[J]. Journal of Chemical Technology and Biotechnology, 2011,86(12): 1 469-1 474.
[35] PARK J S, CHOI J H, YEON K H, et al. An approach to fouling characterization of an ion-exchange membrane using current-voltage relation and electrical impedance spectroscopy[J]. Journal of Colloid and Interface Science, 2006,294(1): 129-138.
[36] 刘璐,赵志娟,李雅,等.工业废水电渗析过程中膜污染研究进展[J]. 过程工程学报, 2015,15(5): 881-891.
[37] HABOVA V, MELZOCH K, RYCHTERA M, et al. Electrodialysis as a useful technique for lactic acid separation from a model solution and a fermentation broth[J]. Desalination, 2004,162(1-3): 361-372.
[38] OTAKI M, TAKIZAWA S, OHGAKI S. Control and modeling of membrane fouling due to microorganism growth by UV pretreatment[J]. Water Science and Technology, 1998,38(4-5): 405-412.
[39] 陈平.电渗析中的膜垢膜污染的防止与清洗[J]. 膜科学与技术, 2000(1): 37.
[40] 荆国林,王晓玉,赵海.电渗析膜污染研究进展[J]. 盐科学与化工, 2006,35(6): 42-46.
[41] TALEBI S, CHEN G Q, FREEMAN B, et al. Fouling and in-situ cleaning of ion-exchange membranes during the electrodialysis of fresh acid and sweet whey[J]. Journal of Food Engineering, 2019,246: 192-199.
[42] KROL J J, WESSLING M, STRATHMANN H. Concentration polarization with monopolar ion exchange membranes: current-voltage curves and water dissociation[J]. Journal of Membrane Science, 1999,162(1-2): 145-154.
[43] LIU Y, YANG S, CHEN Y, et al. Preparation of water-based anion-exchange membrane from PVA for anti-fouling in the electrodialysis process[J]. Journal of Membrane Science, 2019,570: 130-138.
[44] KARKHANECHI H, TAKAGI R, MATSUYAMA H. Biofouling resistance of reverse osmosis membrane modified with polydopamine[J]. Desalination, 2014,336: 87-96.
[45] WANG W Y, FU R Q, LIU Z M, et al. Low-resistance anti-fouling ion exchange membranes fouled by organic foulants in electrodialysis[J]. Desalination, 2017,417: 1-8.
[46] PONTIE M, REJED S BEN, LEGRAND J. Anti-microbial approach onto cationic-exchange membranes[J]. Separation and Purification Technology, 2012,101: 91-97.
[47] HOFFMANN E, YE J, HAHN H H. Recent advances in application of electrodialysis with bipolar membranes for organic acid recovery from fermentation broth[J]. Current Organic Chemistry, 2016,20(26): 2 753-2 761.
[48] DLASK O, N VACLAVIKOVA. Electrodialysis with ultrafiltration membranes for peptide separation[J]. Chemical Papers, 2018,72(2): 261-271.
[49] ZENG G, J YE, M YAN. Application of Electrodeionization Process for Bioproduct Recovery and CO2 Capture and Storage[J]. Current Organic Chemistry, 2016,20(26): 2 790-2 798.
[50] JAROSZEK H, MIKOLAJCZAK W, NOWAK M, et al. Comparison of the applicability of selected anion-exchange membranes for production of sulfuric acid by electro-electrodialysis[J]. Desalination and Water Treatment, 2017, 64: 223-227.
Outlines

/