Food and Fermentation Industries >

2019 , Vol. 45 >Issue 18: 1 - 8

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.021032

In vitro antioxidant and angiotensinz-converting enzyme inhibitory activities of two oligopeptides in Jiupei of Baijiu

  • SUN Jinyuan ,
  • JIANG Yunsong ,
  • LIU Guoying ,
  • LI Hehe ,
  • WU Jihong ,
  • SUN Xiaotao ,
  • SUN Baoguo
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  • 1. Beijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing 100048, China;
    2.Beijing Laboratory for Food Quality and Safety, Beijing Technology and Business University, Beijing 100048, China;
    3.Anhui Gujinggong Co., Ltd., Bozhou 236800, China

Online published: 2019-11-06

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Abstract

In order to trace the source of oligopeptides in Baijiu, Jiupei from Gujinggong was used to isolate oligopeptides and their structures were identified by HPLC-quadrupole-time of flight-MS/MS spectrum (HPLC-Q-TOF-MS/MS). The antioxidant activity and angiotensin-converting enzyme (ACE) inhibitory activity of the oligopeptides were determined in vitro. Two polypeptides, Lys-Gly-Pro (KGP) and Val-Pro-Asp (VPD), were firstly identified and showed strong ABTS radical scavenging ability (1.12 μmol TE/μmol KGP and 1.36 μmol TE/μmol VPD) and oxidative radical absorption capacity (ORAC) (1.11 μmol TE/μmol KGP and 1.17 μmol TE/μmol VPD) compared with standard antioxidant Trolox. KGP and VPD also possessed ACE inhibitory activity with IC50 of 2.91 mmol/L and 2.11 mmol/L, respectively. This study provides a reference for both exploration of bioactive components in Jiupei and improvement of the health function of Baijiu by ameliorating distillation process.

Key words： Jiupei of Baijiu; oligopeptides; antioxidant ability; angiotensin-converting enzyme inhibitor activity

Cite this article

SUN Jinyuan , JIANG Yunsong , LIU Guoying , LI Hehe , WU Jihong , SUN Xiaotao , SUN Baoguo . In vitro antioxidant and angiotensinz-converting enzyme inhibitory activities of two oligopeptides in Jiupei of Baijiu[J]. Food and Fermentation Industries, 2019 , 45(18) : 1 -8 . DOI: 10.13995/j.cnki.11-1802/ts.021032

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