Advances in biological removal of mycotoxins and its mechanism

  • LIU Wei ,
  • XU Xiaofei ,
  • REN Jie ,
  • YANG Jiguo
Expand
  • 1(South China Institute of Collaborative Innovation, Dongguan 523808, China);
    2(College of Food Science and Engineering, South China University of Technology, Guangzhou 510641, China)

Received date: 2019-12-11

  Online published: 2020-05-19

Abstract

Mycotoxins, which have been widely found in food and feed products, were secondary metabolite of fungi and harmful to human and livestock health. Long-term exposure to mycotoxins could lead to liver and kidney damage, canceration, malformation, and immunosuppression. Therefore, a variety of approaches had been explored to eliminate the impact of mycotoxins contamination, including physical, chemical and biological methods. Biological method has been attracting attention because it is environmentally friendly, specific in degradation and mild in reaction conditions. The progress was reviewed in removal of mycotoxins by microorganism. The effect, mechanism and characteristics of the removal of various mycotoxins were summarized, as well as the future research aspect of biological removal was prospected.

Cite this article

LIU Wei , XU Xiaofei , REN Jie , YANG Jiguo . Advances in biological removal of mycotoxins and its mechanism[J]. Food and Fermentation Industries, 2020 , 46(7) : 277 -282 . DOI: 10.13995/j.cnki.11-1802/ts.023058

References

[1] HATHOUT A S, ALY S E. Biological detoxification of mycotoxins: a review [J]. Annals of Microbiology, 2014, 64(3): 905-919.
[2] CAO H, ZHI Y, XU H, et al. Zearalenone causes embryotoxicity and induces oxidative stress and apoptosis in differentiated human embryonic stem cells [J]. Toxicol In Vitro, 2019, 54:243-250.
[3] SCHULZ M C, SCHUMANN L, ROTTKORD U, et al. Synergistic action of the nephrotoxic mycotoxins ochratoxin A and citrinin at nanomolar concentrations in human proximal tubule-derived cells [J]. Toxicol Lett, 2018, 291:149-157.
[4] LUO Y, LIU X, LI J. Updating techniques on controlling mycotoxins-A review [J]. Food Control, 2018, 89:123-132.
[5] GAVAHIAN M, CULLEN P J. Cold plasma as an emerging technique for mycotoxin-free food: Efficacy, mechanisms, and trends [J]. Food Reviews International, 2019,1: 1-22.
[6] PANKAJ S K, SHI H, KEENER K M. A review of novel physical and chemical decontamination technologies for aflatoxin in food [J]. Trends in Food Science & Technology, 2018, 71:73-83.
[7] ALSHANNAQ A, YU J H. Occurrence, toxicity, and analysis of major mycotoxins in food [J]. Int J Environ Res Public Health, 2017, 14(6):632-651.
[8] HASKARD C A, EL-NEZAMI H S, KANKAANPAA P E, et al. Surface binding of aflatoxin B(1) by lactic acid bacteria [J]. Appl Environ Microbiol, 2001, 67(7): 3 086-3 091.
[9] JUODEIKIENE G, BARTKIENE E, CERNAUSKAS D, et al. Antifungal activity of lactic acid bacteria and their application for Fusarium mycotoxin reduction in malting wheat grains [J]. Lwt, 2018, 89:307-314.
[10] NIDERKORN V, MORGAVI D P, ABOAB B, et al. Cell wall component and mycotoxin moieties involved in the binding of fumonisin B1 and B2 by lactic acid bacteria [J]. J Appl Microbiol, 2009, 106(3): 977-985.
[11] KUHARIC Z, JAKOPOVIC Z, CANAK I, et al. Removing aflatoxin M1 from milk with native lactic acid bacteria, centrifugation, and filtration [J]. Arh Hig Rada Toksikol, 2018, 69(4): 334-339.
[12] MARTINEZ M P, MAGNOLI A P, GONZALEZ PEREYRA M L, et al. Probiotic bacteria and yeasts adsorb aflatoxin M1 in milk and degrade it to less toxic AFM1-metabolites [J]. Toxicon, 2019,172:1-7.
[13] CHLEBICZ A, SLIZEWSKA K. In vitro detoxification of aflatoxin B1, deoxynivalenol, fumonisins, T-2 toxin and zearalenone by probiotic bacteria from genus Lactobacillus and Saccharomyces cerevisiae yeast [J]. Probiotics Antimicrob Proteins, 2019.
[14] TAHEUR F B, FEDHILA K, CHAIEB K, et al. Adsorption of aflatoxin B1, zearalenone and ochratoxin A by microorganisms isolated from Kefir grains [J]. Int J Food Microbiol, 2017, 251:1-7.
[15] ZHAI Y, HU S, ZHONG L, et al. Characterization of deoxynivalenol detoxification by Lactobacillus paracasei LHZ-1 isolated from yogurt [J]. J Food Prot, 2019, 82(8): 1 292-1 299.
[16] BEJAOUI H, MATHIEU F, TAILLANDIER P, et al. Ochratoxin A removal in synthetic and natural grape juices by selected oenological Saccharomyces strains [J]. J Appl Microbiol, 2004, 97(5): 1 038-1 044.
[17] ROGOWSKA A, POMASTOWSKI P, WALCZAK J, et al. Investigation of zearalenone adsorption and biotransformation by microorganisms cultured under cellular stress conditions [J]. Toxins (Basel), 2019, 11(8):463-480.
[18] LIEW W P, NURUL-ADILAH Z, THAN L T L, et al. The binding efficiency and interaction of Lactobacillus casei Shirota toward aflatoxin B1 [J]. Front Microbiol, 2018, 9:1 503-1 514.
[19] ARMANDO M R, PIZZOLITTO R P, DOGI C A, et al. Adsorption of ochratoxin A and zearalenone by potential probiotic Saccharomyces cerevisiae strains and its relation with cell wall thickness [J]. J Appl Microbiol, 2012, 113(2): 256-264.
[20] DAWLAL P, BRABET C, THANTSHA M S, et al. Visualisation and quantification of fumonisins bound by lactic acid bacteria isolates from traditional African maize-based fermented cereals, ogi and mahewu [J]. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2019, 36(2): 296-307.
[21] AAZAMI M H, NASRI M H F, MOJTAHEDI M, et al. In vitro aflatoxin B1 binding by the cell wall and (1-->3)-beta-d-Glucan of Baker's Yeast [J]. J Food Prot, 2018, 81(4): 670-676.
[22] SEVIM S, TOPAL G G, TENGILIMOGLU-METIN M M, et al. Effects of inulin and lactic acid bacteria strains on aflatoxin M1 detoxification in yoghurt [J]. Food Control, 2019, 100:235-239.
[23] KROL A, POMASTOWSKI P, RAFINSKA K, et al. Microbiology neutralization of zearalenone using Lactococcus lactis and Bifidobacterium sp.[J]. Anal Bioanal Chem, 2018, 410(3): 943-952.
[24] SHI L, LIANG Z, LI J, et al. Ochratoxin A biocontrol and biodegradation by Bacillus subtilis CW 14 [J]. J Sci Food Agric, 2014, 94(9): 1 879-1 885.
[25] RUIYU Z. Inhibiting Aspergillus flavus growth and degrading aflatoxin B1 by combined beneficial microbes [J]. African Journal of Biotechnology, 2012, 11(65): 12 903-12 909.
[26] GAO X, MA Q, ZHAO L, et al. Isolation of Bacillus subtilis: screening for aflatoxins B1, M1, and G1 detoxification [J]. European Food Research and Technology, 2011, 232(6): 957-962.
[27] RISA A, DIVINYI D M, BAKA E, et al. Aflatoxin B1 detoxification by cell-free extracts of Rhodococcus strains [J]. Acta Microbiol Immunol Hung, 2017, 64(4): 423-438.
[28] MWAKINYALI S E, MING Z, XIE H, et al. Investigation and characterization of Myroides odoratimimus strain 3J2MO aflatoxin B1 degradation [J]. J Agric Food Chem, 2019, 67(16): 4 595-4 602.
[29] LIU D L, YAO D S, LIANG R, et al. Detoxification of aflatoxin B1 by enzymes isolated from Armillariella tabescens [J]. Food Chem Toxicol, 1998, 36(7): 563-574.
[30] ALBERTS J F, GELDERBLOM W C, BOTHA A, et al. Degradation of aflatoxin B(1) by fungal laccase enzymes [J]. Int J Food Microbiol, 2009, 135(1): 47-52.
[31] NAKAZATO M, MOROZUMI S, SAITO K, et al. Interconversion of aflatoxin B1 and aflatoxicol by several fungi [J]. Appl Environ Microbiol, 1990, 56(5): 1 465-1 470.
[32] TAN H, ZHANG Z, HU Y, et al. Isolation and characterization of Pseudomonas otitidis TH-N1 capable of degrading Zearalenone [J]. Food Control, 2015, 47:285-290.
[33] WANG N, LI P, PAN J, et al. Bacillus velezensis A2 fermentation exerts a protective effect on renal injury induced by Zearalenone in mice [J]. Sci Rep, 2018, 8(1): 13 646-13 659.
[34] WANG G, YU M, DONG F, et al. Esterase activity inspired selection and characterization of zearalenone degrading bacteria Bacillus pumilus ES-21 [J]. Food Control, 2017, 77:57-64.
[35] YI P J, PAI C K, LIU J R. Isolation and characterization of a Bacillus licheniformis strain capable of degrading zearalenone [J]. World Journal of Microbiology and Biotechnology, 2010, 27(5): 1 035-1 043.
[36] ZHAO L, JIN H, LAN J, et al. Detoxification of zearalenone by three strains of Lactobacillus plantarum from fermented food in vitro [J]. Food Control, 2015, 54:158-164.
[37] WANG N, WU W, PAN J, et al. Detoxification strategies for zearalenone using microorganisms: A review [J]. Microorganisms, 2019, 7(7): 208-221.
[38] VEKIRU E, HAMETNER C, MITTERBAUER R, et al. Cleavage of zearalenone by Trichosporon mycotoxinivorans to a novel nonestrogenic metabolite [J]. Appl Environ Microbiol, 2010, 76(7): 2 353-2 359.
[39] TINYIRO S E, WOKADALA C, XU D, et al. Adsorption and degradation of zearalenone by Bacillus strains [J]. Folia Microbiol (Praha), 2011, 56(4): 321-327.
[40] BEN SALEM I, BOUSSABBEH M, PIRES DA SILVA J, et al. SIRT1 protects cardiac cells against apoptosis induced by zearalenone or its metabolites alpha- and beta-zearalenol through an autophagy-dependent pathway [J]. Toxicol Appl Pharmacol, 2017, 314:82-90.
[41] HARTINGER D, MOLL W. Fumonisin elimination and prospects for detoxification by enzymatic transformation [J]. World Mycotoxin Journal, 2011, 4(3): 271-283.
[42] ZHAO Z, ZHANG Y, GONG A, et al. Biodegradation of mycotoxin fumonisin B1 by a novel bacterial consortium SAAS79 [J]. Appl Microbiol Biotechnol, 2019, 103(17): 7 129-7 140.
[43] RODRIGUEZ H, REVERON I, DORIA F, et al. Degradation of ochratoxin a by Brevibacterium species [J]. J Agric Food Chem, 2011, 59(19): 10 755-10 760.
[44] VARGA J, PETERI Z, TABORI K, et al. Degradation of ochratoxin A and other mycotoxins by Rhizopus isolates [J]. Int J Food Microbiol, 2005, 99(3): 321-328.
[45] CHEN W, LI C, ZHANG B, et al. Advances in biodetoxification of ochratoxin A-A review of the past five decades [J]. Front Microbiol, 2018, 9:1 386.
[46] CHANG X, WU Z, WU S, et al. Degradation of ochratoxin A by Bacillus amyloliquefaciens ASAG1 [J]. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 32(4): 564-571.
[47] ZHANG X, YANG H, APALIYA M T, et al. The mechanisms involved in ochratoxin A elimination by Yarrowia lipolytica Y-2 [J]. Annals of Applied Biology, 2018, 173(2): 164-174.
[48] LOI M, FANELLI F, LIUZZI V C, et al. Mycotoxin biotransformation by native and commercial enzymes: Present and future perspectives [J]. Toxins (Basel), 2017, 9(4):111.
[49] GAO X, MU P, WEN J, et al. Detoxification of trichothecene mycotoxins by a novel bacterium, Eggerthella sp. DII-9 [J]. Food Chem Toxicol, 2018, 112:310-319.
[50] ISLAM R, ZHOU T, YOUNG J C, et al. Aerobic and anaerobic de-epoxydation of mycotoxin deoxynivalenol by bacteria originating from agricultural soil [J]. World J Microbiol Biotechnol, 2012, 28(1): 7-13.
[51] HE W J, YUAN Q S, ZHANG Y B, et al. Aerobic de-epoxydation of trichothecene mycotoxins by a soil bacterial consortium isolated using in situ soil enrichment [J]. Toxins (Basel), 2016, 8(10): 277-289.
[52] QU R, JIANG C, WU W, et al. Conversion of DON to 3-epi-DON in vitro and toxicity reduction of DON in vivo by Lactobacillus rhamnosus [J]. Food Funct, 2019, 10(5): 2 785-2 796.
[53] PETCHKONGKAEW A, TAILLANDIER P, GASALUCK P, et al. Isolation of Bacillus spp. from Thai fermented soybean (Thua-nao): screening for aflatoxin B1 and ochratoxin A detoxification [J]. J Appl Microbiol, 2008, 104(5): 1 495-1 502.
Outlines

/