The type 1 diabetic rats were used to investigate the immune regulation and antioxidant activity of raspberry pulp polysaccharide (RPP). The results showed that the RPP could significantly lower blood glucose of diabetic rats induced by streptozotocin (STZ), maintain their weight and restore the damaged islet in diabetic rats via significantly decreasing the concentration of CD4, CD8, TNF-α, IFN-γ, IL-2, IgA, IgG, IgE and IgM, increasing the activities of SOD and GSH-PX in serum and pancreas of diabetic rats and reducing the content of MDA. In summary, RPP can improve the damage of islet β cells, showing a good activity in the treatment of type 1 diabetes.
TIAN Wenhui
,
YANG Yongjing
,
WU Yun
,
CHEN Wei
. Immune regulation and antioxidant activity of raspberry pulp polysaccharide through type 1 diabetic rats[J]. Food and Fermentation Industries, 2020
, 46(12)
: 102
-108
.
DOI: 10.13995/j.cnki.11-1802/ts.023340
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