In this study, the biological characteristics of 12 Lactobacillus plantarum strains were evaluated, including their growth rate, ability of acid production, adhesion to HT-29 cells, ability to form biofilms, surface hydrophobicity, and acid and bile salt resistance. Meanwhile, these strains were administered to Campylobacter jejuni and Toxoplasma gondii co-infected mice by gavage. The results showed that Lactobacillus plantarum N36 and ZL4 could significantly reduce the transcriptional activities of Campylobacter jejuni virulence genes. The correlation analysis of biological characteristics of Lactobacillus plantarum and the transcriptional activities of Campylobacter jejuni virulence genes showed that the high cell adhesion caused by the high surface hydrophobicity on bacterial body and the strong biofilm formation ability of the strains could significantly reduce the virulence genes transcriptional activities of Campylobacter jejuni in mice.
JIN Xing
,
HE Yufeng
,
ZHOU Yonghua
,
CHEN Xiaohua
,
WANG Gang
,
ZHAO Jianxin
,
ZHANG Hao
,
CHEN Wei
. Lactobacillus plantarum with high cell adhesion and biofilm formation ability effectively inhibits the transcriptional activities of Campylobacter jejuni virulence genes in mice[J]. Food and Fermentation Industries, 2020
, 46(14)
: 12
-18
.
DOI: 10.13995/j.cnki.11-1802/ts.023559
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