Food and Fermentation Industries >

2020 , Vol. 46 >Issue 19: 295 - 300

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.024581

Research progress on detection methods of amanita cyclopeptide toxins

  • ZHANG Xiaomeng ,
  • QIN Mingwei ,
  • ZHAO Xinyue ,
  • SONG Yuzhu ,
  • ZHANG Jinyang ,
  • XIA Xueshan ,
  • HAN Qinqin
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  • (Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China)

Received date: 2020-05-28

  Revised date: 2020-06-15

  Online published: 2020-11-02

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Abstract

Amatoxins have extremely strong toxicity as one of the top ten deadly poisons. Mushrooms containing amatoxins play a highly significant role in mushroom poisoning, which lead to 90% of the deaths. Amatoxins poisoning can give rise to acute liver damage and multiple organ failure. What is worse, it has not yet found a specific antidote. So amatoxins are high-risk toxins that have attracted the attention of local food safety monitoring in various countries around the world and it is important to master the high-speed detection technology and method of amatoxins. Based on the introduction of the molecular structure, physical and chemical properties of amatoxins and their impact on humans, this article introduces the rapid detection methods of amatoxins worldwide. The conventional detection methods consist of enzyme-linked immunosorbent assay, lateral flow immunoassay, high performance liquid chromatography, liquid chromatography-mass spectrometry. Moreover, the utilization of hyper branched branched rolling circle amplification and molecular imprinting technique widen the views of amatoxins detection. These detection methods will present various advantages and disadvantages in distinct experimental environments and each has its own applicable conditions. For example, some detection methods are suitable for rapid detection of mushroom samples and some are more suitable for on-site detection. By comparing different characteristics of these methods, it provide an important reference for the laboratory or clinic to establish a more convenient, rapid and sensitive method for detecting amatoxins

Key words： mushroom poisoning; amatoxins; rapid detection; on-site detection; lateral flow immunoassay

Cite this article

ZHANG Xiaomeng , QIN Mingwei , ZHAO Xinyue , SONG Yuzhu , ZHANG Jinyang , XIA Xueshan , HAN Qinqin . Research progress on detection methods of amanita cyclopeptide toxins[J]. Food and Fermentation Industries, 2020 , 46(19) : 295 -300 . DOI: 10.13995/j.cnki.11-1802/ts.024581

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