An analytical method for the determination of erucamide (EAD) and oleamide (OAD) in aluminum-plastic compound film by liquid chromatography-triple quadrupole tandem mass spectrometry was established. Under the optimized spectrometry conditions, chromatographic columns and mobile phases, the positive aluminum-plastic compound film was used to optimize the sample pretreatment method, extraction solvent and extraction time. And 11 types of aluminum-plastic compound film on the market were determined. The results showed that the optimum condition for the detection of EAD and OAD was as follows: Ethanol was used as extraction solvent; ultrasonic was performed for 60 min and the extraction was repeated twice; Poroshell 120EC-C8 (100 mm×3.0 mm, 2.7 μm) was used with pure methanol as mobile phase. There were good linear relationships with their correlation coefficients(R2) all greater than 0.995 for EAD and OAD in the concentration of 0.1-3.0 mg/L. And the detection limits were all less than 0.02 mg/L and quantitative limits were less than or equal to 0.05 mg/L. The average recoveries were 82%-116% with the relative standard deviation (RSD) were 4.1%-9.3% (n=6). EAD could be detected in all 11 samples while OAD only could be detected in 5 samples. So the method developed here is easy to operate with low detective limit, which could provide a reference for the qualitative and quantitative detection of EAD and OAD in aluminum-plastic compound film.
MENG Fangling
,
HU Changying
,
LI Zicheng
,
WANG Zhiwei
. Determination of erucamide and oleamide in aluminum-plastic compound film by liquid chromatography tandem mass spectrometry[J]. Food and Fermentation Industries, 2020
, 46(20)
: 208
-213
.
DOI: 10.13995/j.cnki.11-1802/ts.024564
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