The optimum ultrasonic extraction process of proanthocyanidins was studied.Optimal extracting condition was confirmed as follows: the rate of power of ultrasonic was 100%,alcohol content was 70%,the ratio of liquid to material was 1∶12,the extraction time was 15mins and the extraction temperature was 45℃.Choose LS300 resin as the material for the purification.The absorbability of LS300 resin was studied.The results of static adsorption showed that the adsorption isotherm could be correlated with Freundlich.The adsorption equilibrium time was about 5h.The experiment of concentration gradient elution by ethanol solution showed that the most proanthocyanidins were concentrated on two parts: the 20% and 40%.The mass fractions of two parts were 86.5% and 92.3%.