In this study,channel catfish skins were dried with three different methods: air dry at room temperature,hot air dry and marinated with salt.The treated samples were preserved at room temperature for 10 days,30 days,60 days and 90 days.Channel catfish skin shrinkage temperature were measured by differential calorimetry(DSC) method.Collagens of those fish skins were extracted.The molecular weight distributions were determined by SDS-PAGE,and the Fourier Transform Infrared Spectroscopies of the collagens were also studied.The results showed that natural drying was the best treatment for fish skin preservation.