Food and Fermentation Industries >

2011 , Vol. 37 >Issue 05: 115 - 117

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.2011.05.015

Food and Fermentation Industries

Study on the α-glucosidase Inhibitor from Alisma orientalis

  • Yi Xing ,
  • Zhong Qiu-chen ,
  • Jiao Shuang ,
  • Zhang Jian-ping ,
  • Xiao Xiao-nian
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Online published: 2011-05-25

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Abstract

The sequential extractions using petroleum ether,ethyl acetate and n-butanol were applied to water extract of Alisma orientale.The aqueous phase was added on a column of macroporous resin and was washed with distilled water and 95%ethanol,successively.In addition,the inhibitory activity against α-glucosidase of each fraction was determined and the inhibitory kinetics of the fraction with the strongest inhibitory activities was investigated.The results showed that the fraction with the strongest inhibitory activities was n-butanol fraction,a kind of non-competition inhibitor with inhibitory ratio of 92.30%.

Key words： Alisma orientalis; extract; α-glucosidase; inhibition; diabetes mellitus

Cite this article

Yi Xing , Zhong Qiu-chen , Jiao Shuang , Zhang Jian-ping , Xiao Xiao-nian . Study on the α-glucosidase Inhibitor from Alisma orientalis[J]. Food and Fermentation Industries, 2011 , 37(05) : 115 -117 . DOI: 10.13995/j.cnki.11-1802/ts.2011.05.015

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