A method for determining the residues of buprofezin,chlorpyrifos,acetamiprid,omethoate,dimethoate and carbendazim in tea by high performance liquid chromatogram(HPLC) tandem time-of-flight(TOF) MS was developed.Tea samples were extracted by acidic acetonitrile,cleaned up by matrix solid-phase dispersion and detected by HPLC-TOF MS.The method presented a good linear relation linear correlation(R2=0.995～0.999) with the concentration ranged from 1 to 50 μg/kg.Limits of detection varied with different pesticides could be measured at 0.01～1 μg/kg,the average recoveries ranged from 70% to 102% and relative standard deviation(RSD) was between 4%～6%.The method is fast,accurate and reliable and suitable for quantitative and qualitative detection of pesticide residues in tea.