The method of hydrochloric acid solution immersion was employed in extracting phytic acid and synchronously inactivating lipase in full-fat rice bran. The impact of acid concentration,temperature,time and solid to liquid ratio on phytic acid yield and residual lipase activity were studied. The best immersion conditions were obtained by orthogonal and verification experiment as follows: acid concentration 1. 2%,temperature 50 ℃,time 4 h and solid to liquid ration 1∶ 10. Under these conditions,the yield of phytic acid was 4. 63% and the lipase activity was reduced by 93. 6%.