The migration rates of bisphenol A from PC in the distilled water,tap water and mineral water were determined under microwave heating and constant temperature heating by high performance liquid chromatograph fluorescence detector The results showed that the migration rates of bisphenol A increased with the increasing of heating time under both heating methods. Among three different types of water,the migration rate of bisphenol A in the distilled water was the lowest. The equilibrium time of the migration by the microwave heating was nearly 12 times shorter than that by constant temperature heating. This indicated that the migration rates of harmful substances in the plastic were accelerated under the microwave heating process. As a result,the migration test time was saved and the cost was reduced. There was no obvious difference in maximum migration rates of bisphenol A in the distilled water and tap water between two heating methods( P > 0. 05). The maximum migration rate of bisphenol A in the mineral water by the microwave heating was higher than that by the constant temperature heating( P < 0. 01). Therefore,when the food was heated by the microwave heating,the heating time should be paid more attention due the food properties in order to minimize the migration of bisphenol A from PC to the food.