Pichia pastoris(P.pastoris) is a potential microbial cell factory for its high-level heterologous proteins production and metabolties accumulation.Literature analysis was a good tool to understand the situation about the whole P.pastoris research.Literature about P.pastoris from Web of Science database was organized according to publication time,countries,etc to show the situation of China in this field.At the same time,the emerging research opportunities,such as genetic manipulation,fermentation strategies,pexophagy,were reviewed for research work at next stage.