Recent advances on cellobiose 2-epimerase

  • XU Zheng ,
  • ZHU Yafeng
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  • (College of Food Science and Light Industry,Nanjing Technology University,Nanjing 211816,China)

Received date: 2020-05-18

  Revised date: 2020-06-15

  Online published: 2020-12-30

Abstract

Cellobiose 2-epimerase has attracted growing attentions as an industrial enzyme.It was applied to lactulose bio-production,as well asD-mannose preparation.Lactulose was used for treating constipation and hepatic encephalopathy as a common over-the-counter drug,and showing a high efficiency.The annual global demand for lactulose was nearly 100 000 tons,showing great commercial value.In this review,recent advances in new enzyme characterization,protein engineering and enzyme immobilization for cellobiose 2-epimerase are summarized,which would shed light on researches in this field.

Cite this article

XU Zheng , ZHU Yafeng . Recent advances on cellobiose 2-epimerase[J]. Food and Fermentation Industries, 2020 , 46(23) : 248 -254 . DOI: 10.13995/j.cnki.11-1802/ts.024471

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