Food and Fermentation Industries >

2022 , Vol. 48 >Issue 1: 117 - 123

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.028972

Effects of biomimetic digestion on composition and antioxidant activity of alcohol extracts from Lonicera japonica Thunb. in vitro

  • SUN Chunyong ,
  • WANG Lingna ,
  • YAN Peizheng ,
  • ZHANG Yongqing ,
  • LI Jia ,
  • ZHAO Dongsheng
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  • (School of Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

Received date: 2021-08-10

  Revised date: 2021-09-18

  Online published: 2022-01-27

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Abstract

The aim of this study was to explore the changes of chemical components and antioxidant activities in alcohol extracts from Lonicera japonica Thunb. during biomimetic digestion in vitro. There were twelve compounds in alcohol extract from L.japonica, and the following index which including total antioxidant capacity, hydroxyl radical scavenging rate, and DPPH radical scavenging rate before and after gastrointestinal digestion were determined. The results showed that the contents of phenolic acid were decreased with the extension of simulated gastric digestion time, but there was no significant change in simulated intestinal digestion (P>0.05). The contents of flavonoids increased at first and then decreased, but there was no significant change in the simulated intestinal digestion process (P>0.05). However, before and after bionic digestion, no significant change was found in the content of iridoids in garland (P>0.05). After simulated stomach and intestinal digestion, the total antioxidant capacity and the scavenging rate to hydroxyl radical (·OH) and ·DPPH radical of the digested products were significantly decreased (P<0.05) which with a strong correlation (P<0.05). The gastric and intestinal environment can promote the degradation of phenolic acids and flavonoids in L.japonica, and significantly reduce their antioxidant activity. This study provides theoretical reference for further research on the digestive process of L.japonica in vivo.

Key words： Lonicera japonica Thunb.; alcohol extract; chemical component; biomimetic digestion; antioxidant activity

Cite this article

SUN Chunyong , WANG Lingna , YAN Peizheng , ZHANG Yongqing , LI Jia , ZHAO Dongsheng . Effects of biomimetic digestion on composition and antioxidant activity of alcohol extracts from Lonicera japonica Thunb. in vitro[J]. Food and Fermentation Industries, 2022 , 48(1) : 117 -123 . DOI: 10.13995/j.cnki.11-1802/ts.028972

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