Food and Fermentation Industries >

2022 , Vol. 48 >Issue 1: 301 - 307

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.026973

Research progress of Vibrio parahaemolyticus virulence factors and drug resistance mechanism

  • ZHANG Jian ,
  • ZHU Qiuhua ,
  • ZHANG Ming ,
  • WANG Liwei ,
  • DONG Hao ,
  • ZENG Xiantong ,
  • BAI Wutong ,
  • GUO Xiaohua ,
  • SHEN Zhaohua ,
  • SONG Gang ,
  • ZHANG Defu ,
  • LI Jianrong
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  • 1(College of Food Science and Technology,Institute of Ocean,Bohai University;Food Safety Key Lab of Liaoning Province;National and Local Joint Engineering Research Center of Storage,Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products,Jinzhou 121013,China)
    2(State Key Laboratory of Biochemical Engineering,Institute of Process Engineering, Chinese Academy of Sciences,Beijing 100190,China)
    3(Shandong Meijia Group Co.Ltd.,Rizhao 276806,China)
    4(Jinzhou Longhaixingang Science and Technology Co.Ltd.,Jinzhou 121211,China)
    5(Linghai Dalian Seafood Process Co.Ltd.,Jinzhou 121211,China)

Received date: 2021-02-03

  Revised date: 2021-05-24

  Online published: 2022-01-27

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Abstract

Vibrio parahaemolyticus is one of the main pathogenic bacteria in aquatic products.It can cause diseases and deaths of aquaculture products,as well as gastroenteritis and other diseases in humans.It not only has potential food safety hazards,but also poses potential hazards to human health.This article mainly describes the virulence factor tdh of V.parahaemolyticus and the mechanism of the type III secretion system(T3SS),T3SS1 and T3SS2 in the strains,and five mechanisms of V.parahaemolyticus resistance to drugs were reviewed:production of biofilm,plasmid mediated drug resistance,the production of inactivated or inactivated enzymes,the efflux pump,and the change of drug targets.

Key words： Vibrio parahaemolyticus; thermoslable direct hemolysin(TDH); T3SS; mechanism of drug resistance; plasmid

Cite this article

ZHANG Jian , ZHU Qiuhua , ZHANG Ming , WANG Liwei , DONG Hao , ZENG Xiantong , BAI Wutong , GUO Xiaohua , SHEN Zhaohua , SONG Gang , ZHANG Defu , LI Jianrong . Research progress of Vibrio parahaemolyticus virulence factors and drug resistance mechanism[J]. Food and Fermentation Industries, 2022 , 48(1) : 301 -307 . DOI: 10.13995/j.cnki.11-1802/ts.026973

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