[1] 刘铭, 刘玉环, 王允圃, 等.制备、纯化和鉴定生物活性肽的研究进展及应用[J].食品与发酵工业, 2016, 42(4):244-251.
LIU M, LIU Y H, WANG Y P, et al.Research progress on production, purification and identification of bioactive peptides and its challenges in application[J].Food and Fermentation Industries, 2016, 42(4):244-251.
[2] CHOKSAWANGKARN W, PHIPHATTANANUKOON S, JARESITTHIKUNCHAI J, et al.Antioxidative peptides from fish sauce by-product:Isolation and characterization[J].Agriculture and Natural Resources,2018,52(5):460-466.
[3] 杨萍, 柯虹乔, 章超桦, 等.大眼金枪鱼头蛋白酶解物1ku超滤组分的抗氧化活性及其理化性质[J].水产学报, 2012, 36(8):1 297-1 303.
YANG P, KE H Q, ZHANG C H, et a1.Antioxidant activity and physicochemical properties of 1 ku fraction by ultrafiltration of bigeye tuna (Thunnus obesus) head protein hydrolysate[J].Journal of Fisheries of China, 2012, 36(8):1 297-1 303.
[4] LEE S H, QIAN Z J, KIM S K.A novel angiotensin I converting enzyme inhibitory peptide from tuna frame protein hydrolysate and its antihypertensive effect in spontaneously hypertensive rats[J].Food Chemistry,2010,118(1):96-102.
[5] LIU Z Y, DONG S Y, XU J, et al.Production of cysteine-rich antimicrobial peptide by digestion of oyster (Crassostrea gigas) with alcalase and bromelin[J].Food Control, 2008, 19(3):231-235.
[6] CHALAMAIAH M, JYOTHIRMAYI T, DIWAN P V, et al.Antiproliferative, ACE-inhibitory and functional properties of protein hydrolysates from rohu (Labeo rohita) roe (egg) prepared by gastrointestinal proteases[J].Journal of Food Science and Technology, 2015, 52(12):8 300-8 307.
[7] SONG R,WEI R B, LUO H Y, et al.Isolation and identification of an antiproliferative peptide derived from heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)[J].Journal of Functional Foods,2014,10:104-111.
[8] 王波, 韩立民.我国贝类养殖发展的基本态势与模式研究[J].中国海洋大学学报(社会科学版),2017(3):5-12.
WANG B, HAN L M.A Study on the basic situation and pattern of shellfish breeding in China[J].Journal of Ocean University of China (Social Sciences),2017(3):5-12.
[9] 张彩梅, 刘晓萍, 张红梅, 等.扇贝多肽对小鼠非特异性免疫功能的调节作用[J].中国海洋药物,2006,25(5):38-40.
ZHANG C M, LIU X P, ZHANG H M, et al.Effect of PCF on the nonspecific immunity in mice[J].Chinese Journal of Marine Drugs,2006,25(5):38-40.
[10] 叶盛旺, 杨最素, 李维, 等.青蛤酶解多肽对RAW264.7巨噬细胞的免疫调节作用[J].食品科学,2019,40(7):185-191.
YE S W, YANG Z S, LI W, et al. Immunomodulatory effects of peptides from enzymatic hydrolysate of cyclina sinensis on RAW264.7 macrophages[J].Food Science,2019,40(7):185-191.
[11] KIM Y S, AHN C B, JE J Y.Anti-inflammatory action of high molecular weight mytilus edulis hydrolysates fraction in LPS-induced RAW264.7 macrophage via NF-κB and MAPK pathways[J].Food Chemistry,2016,202:9-14.
[12] WANG Y K, HE H L, WANG G F, et al.Oyster(Crassostrea gigas) hydrolysates produced on a plant scale have antitumor activity and immunostimulating effects in BALB/c mice[J].Marine Drugs,2010,8(2):255-268.
[13] 陈利梅, 周文化.我国海洋食品工业的现状及对其发展的思考[J].食品与药品,2005,7(7):22-25.
CHEN L M, ZHOU W H.Status and ideas on the development of marine food[J].Food and Drug,2005,7(7):22-25.
[14] 纪丽娜. 金枪鱼头酶解物免疫活性肽的分离及对小鼠腹腔巨噬细胞功能的影响[D].湛江:广东海洋大学, 2012.
JI L N.Studies on separation of immune activity from tuna head hydrolysates and its effect on mouse peritioneal macrophages[D].Zhanjiang: Guangdong Ocean University,2012.
[15] 袁学文, 王炎冰.远东拟沙丁鱼低聚肽化学组成及其增强免疫力功能评价[J].食品与发酵工业,2018,44(4):104-110.
YUAN X W, WANG Y B.Chemical composition of oligopeptide from Sardinops agax and its immunoregulatory activity evaluation[J].Food and Fermentation Industries,2018,44(4):104-110.
[16] CHALAMAIAH M, HEMALATHA R F, JYOTHIRMAYI T, et al.Immunomodulatory effects of protein hydrolysates from rohu (Labeo rohita) egg (roe) in BALB/c mice[J].Food Research International, 2014, 62(8):1 054-1 061.
[17] HOU H, FAN Y, LI B F, et al.Preparation of immunomodulatory hydrolysates from Alaska pollock frame[J].Journal of the Science of Food and Agriculture,2012,92(15):3 029-3 038.
[18] YANG R Y, PEI X R, WANG J B, et al.Protective effect of a marine oligopeptide preparation from Chum Salmon (Oncorhynchus keta) on radiation-induced immune suppression in mice[J].Journal of the Science of Food Agriculture, 2010, 90(13):2 241-2 248.
[19] 卢连华, 周景洋, 颜燕, 等.海参肽对小鼠免疫调节及抗疲劳能力的影响[J].山东医药,2009,49(25):35-37.
LU L H, ZHOU J Y, YAN Y, et al.Effects of sea cucumber peptide on the immune regulation and anti-fatigue ability of mice[J].Shandong Medicine Journal,2009,49(25):35-37.
[20] 何丽霞, 陈启贺, 刘睿, 等.海参寡肽免疫调节作用及机制研究[J].科技导报,2016,34(11):42-47.
HE L X, CHEN Q H, LIU R, et al.Sea cucumber oligopeptides:Immunomodulatory effects and its mechanism[J].Science & Technology Review,2016,34(11):42-47.
[21] CIAN R E, LÓPEZ-POSADAS R, DRAGO S R, et al.A porphyra columbina hydrolysate upregulates IL-10 production in rat macrophages and lymphocytes through an NF-κB, and p38 and JNK dependent mechanism[J].Food Chemistry, 2012, 134(4):1 982-1 990.
[22] 郭昱, 吴梧桐, 巫冠中.鲨肝肽对小鼠免疫性肝损伤的保护作用及免疫调节作用[J].中国新药杂志,2001,10(1):29-31.
GUO Y, WU W T, WU G Z.The liver-protective and immunomodulative effect of Shahepatide in mice with immune liver injury[J].Chinese Journal of New Drugs,2001,10(1):29-31.
[23] CARRASCO-CASTILLA J, HERNÁNDEZ-ÁLVAREZ A J, JIMNEZ-MARTNEZ C, et al.Use of proteomics and peptidomics methods in food bioactive peptide science and engineering[J].Food Engineering Reviews, 2012, 4(4):224-243.
[24] 邓志程, 张迪, 吉宏武, 等.马氏珠母贝免疫活性肽的纯化与鉴定[J].广东海洋大学学报,2017,37(4):78-86.
DENG Z C, ZHANG D, JI H W, et al.Purification and identification of immunomodulating peptides from enzymatic hydrolysates of pinctada martensi[J].Journal of Guangdong Ocean University,2017,37(4):78-86.
[25] 胡旭阳, 李维, 孔祥东, 等.响应面法优化日本黄姑鱼鱼肉免疫活性肽的提取工艺[J].食品工业科技,2019,40(17):173-178.
HU X Y, LI W, KONG X D, et al.Optimization of extraction technology of immunologically active peptides from Nibea Japonica by response surface methodology[J].Science and Technology of Food Industry,2019,40(17):173-178.
[26] 王敏, 卢赛, 张曾亮, 等.鲍鱼水解肽的抗氧化、抗炎及免疫调节作用[J].食品工业科技,2021,42(5):282-288.
WANG M, LU S, ZHANG Z L, et al.Antioxidant,anti-inflammatory and immunomodulatory effects of abalone hydrolytic peptide[J].Science and Technology of Food Industry,2021,42(5):282-288.
[27] 蔡本利, 洪鹏志, 杨萍, 等.黄鳍金枪鱼头蛋白酶解液对小鼠免疫功能的调节作用[J].天然产物研究与开发,2007,19(5):791-795.
CAI B L, HONG P Z, YANG P, et al.Effect of enzyme hydrolyzed protein of tuna head on immune function of mice[J].Natural Product Research and Development,2007,19(5):791-795.
[28] DUARTE J, VINDEROLA G, RITZ B, et al.Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation[J].Immunobiology, 2006, 211(5):341-350.
[29] 蒋定文, 沈先荣, 贾福星, 等.海洋星虫提取物的营养分析及免疫调节作用的初步观察[J].中国生化药物杂志, 2004,24(2):96-97.
JIANG D R, SHEN X R, JIA F X, et al.Nutrient analysis and immune regulation study on extract of sipunculidae[J].Chinese Journal of Biochemical Pharmaceutics, 2004,24(2):96-97.
[30] 李婉, 曹文红, 章超桦, 等.牡蛎酶解产物的组成特点及其体外免疫活性[J].食品工业科技, 2017,38(16):35-42.
LI W, CAO W H, ZHANG C H, et al. Composition characteristics of oyster enzymatic hydrolysate and its immune activity in vitro[J].Science and Technology of Food Industry, 2017,38(16):35-42.
[31] 丁霈希, 章超桦, 高加龙, 等.等边浅蛤肉酶解产物超滤组分免疫调节作用[J].广东海洋大学学报,2020,40(3):114-121.
DING P X, ZHANG C H, GAO J L, et al.Immunomodulatory effects of the ultrafiltration fractions of enzymatic hydrolysates from the edible part of Gomphina aequilatera[J].Journal of Guangdong Ocean University,2020,40(3):114-121.
[32] 何小庆. 波纹巴非蛤活性肽的酶法制备及其免疫活性的研究[D].湛江:广东海洋大学,2014.
HE X Q.Enzymatic preparation and immunocompetence research of Paphia undulata peptides[D].Zhanjiang:Guangdong Ocean University,2014.
[33] 冯晓梅, 韩玉谦, 赵志强, 等.牡蛎酶解产物中多肽的分离纯化及其结构研究[J].中国海洋药物,2009,28(2):1-5.
FENG X M, HAN Y Q, ZHAO Z Q, et al.Study of isolation, preparation and structure identification of peptides from hydrolyzates of oyster[J].Chinese Journal of Marine Drugs,2009,28(2):1-5.
[34] XU B G, YE L, TANG Y P, et al.Preparation and purification of an immunoregulatory peptide from Stolephorus chinensis of the East Sea of China[J].Process Biochemistry 2020, 98:151-159.
[35] NGUYEN H T M, SYLLA K S B, RANDRIAMAHATODY Z, et al.Enzymatic hydrolysis of yellowfin tuna(Thunnus albacares) by-products using protamex protease[J].Food Technology and Biotechnology, 2011, 49(1):48-55.
[36] 左爱华, 王祖哲, 马普, 等.海参低聚肽的高通量HPLC-MS/MS分析鉴定和活性筛选[J].食品工业科技,2020,41(3):1-5;11.
ZUO A H, WANG Z Z, MA P, et al.Analysis, Identification and activity screening of apostichopus japonicus oligopeptides by high throughput of HPLC-MS/MS[J].Science and Technology of Food Industry,2020,41(3):1-5;11.
[37] ZHENG Y J, ZHANG Y F, SAN S.Efficacy of a Novel ACE-inhibitory peptide from Sargassum maclurei in hypertension and reduction of intracellular endothelin-1[J].Nutrients, 2020, 12(3):653-668.
[38] LEE S J, KIM E K, KIM Y S, et al.Purification and characterization of a nitric oxide inhibitory peptide from Ruditapes philippinarum[J].Food and Chemical Toxicology, 2012, 50(5):1 660-1 666.
[39] 牛瑞, 于建生.鳕鱼多肽的抗氧化活性及其分离纯化[J].食品与生物技术学报,2010,29(4):562-566.
NIU R, YU J S.Antioxidant activity and purification of pollock peptides[J].Journal of Food Science and Biotechnology,2010,29(4):562-566.
[40] 任娇艳, 张榕, 杨继国, 等.柴鱼蛋白肽的酶法制备、分离纯化及结构鉴定[J].现代食品科技,2015,31(9):155-161.
REN J Y, ZHANG R, YANG J G, et al.Enzymatic preparation, separation, and structural identification of bonito protein hydrolysates[J].Modern Food Science & Technology,2015,31(9):155-161.
[41] 蔡康鹏, 蔡水淋, 吴靖娜, 等.海洋贝类活性肽研究进展[J].渔业研究,2016,38(2):157-164.
CAI K P, CAI S H, WU J G, et al.Functional and bioactive properties of marine shellfish derived peptides:A review[J].Journal of Fisheries Research,2016,38(2):157-164.
[42] HERNÁNDEZ-LEDESMA B, QUIRÓS A, AMIGO L, et al.Identification of bioactive peptides after digestion of human milk and infant formula with pepsin and pancreatin[J].International Dairy Journal,2007,17(1):42-49.
[43] CHI C F, HU F Y, WANG B, et al.Antioxidant and anticancer peptides from the protein hydrolysate of blood clam (Tegillarca granosa) muscle[J].Journal of Functional Foods,2015,15:301-313.
[44] 李建杰,叶磊,荣瑞芬.生物活性肽的酶法制备及分离鉴定研究进展[J].食品研究与开发,2012,33(2):195-199.
LI J J, YE L, RONG R F.Research advances on enzymatic preparation and separation identification of bioactive peptides[J].Food Research and Development,2012,33(2):195-199.
[45] AHN C B,CHO Y S,JE J Y.Purification and anti-inflammatory action of tripeptide from salmon pectoral fin byproduct protein hydrolysate[J].Food Chemistry, 2015,168:151-156.
[46] HE X Q, CAO W H, PAN G K, et al.Enzymatic hydrolysis optimization of Paphia undulata and lymphocyte proliferation activity of the isolated peptide fractions[J].Journal of the Science of Food and Agriculture,2015, 95(7):1 544-1 554.
[47] LI W, YE S W, ZHANG Z W, et al.Purification and characterization of a novel pentadecapeptide from protein hydrolysates of Cyclina sinensis and its immunomodulatory effects on RAW264.7 cells[J].Marine Drugs,2019,17(1):30-46.
[48] KIM E K, KIM Y S, HWANG J W, et al.Purification of a novel nitric oxide inhibitory peptide derived from enzymatic hydrolysates of Mytilus coruscus[J].Fish and Shellfish Immunology,2013,34(6):1 416-1 420.