In this study, magnetic nanoparticles loaded octadecylamine functionalized mesoporous carbon composites were independently developed and a sample pretreatment method for rapid detection of organophosphorus pesticide residues in green leafy vegetables based on QuEChERS technology and gas chromatography-mass spectrometry was developed. The surface structure of the magnetic mesoporous composite was characterized by transmission electron microscopy, X-ray diffraction, magnetometer and nitrogen adsorption-desorption. The experimental results showed that compared with the traditional purification agent, the magnetic mesoporous material could eliminate the matrix interference, improve the detection efficiency. In addition, the operation was simple. The residues of 16 organophosphorus pesticides in green leafy vegetables ranged from 0.02-0.25 μg/mL with the correlation coefficient (R2) of 0.994 3-0.999 7. The average recoveries of 16 organophosphorus pesticides in green leafy vegetables were 81.3%-94.0% at the levels of 0.02, 0.05 and 0.10 mg/kg, and the relative standard deviations were less than 10%. The detection limits were 0.01-0.08 μg/mL. Then, the method was applied to detect green leafy vegetables. The results showed that all green leafy vegetables met the maximum residue limit of organophosphorus pesticides. This method has the advantages of high sensitivity, strong universality, high accuracy, good stability, economic and environmental protection, and is suitable for the pretreatment of pesticide residues in other vegetables and fruits.
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