Food and Fermentation Industries >

2022 , Vol. 48 >Issue 12: 316 - 323

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.029394

Research progress of immunology-based microfluidic chip for rapid detection of pathogens

  • LI Bin ,
  • LIU Cheng ,
  • TIAN Yachen ,
  • LIU Qing ,
  • LI Daixi ,
  • HUANG Xiaotian ,
  • LIU Tao ,
  • YANG Hao
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  • (School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China)

Received date: 2021-09-16

  Revised date: 2021-10-19

  Online published: 2022-07-15

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Abstract

Food safety has always received great attention from people, early and rapid detection of pathogenic microorganisms can avoid large-scale outbreaks of food-borne diseases. The microfluidic detection chip based on immunology is a sensitive, simple and easy-to-use detection platform, which has been widely used in the rapid detection of pathogenic microorganisms. Compared with traditional immunological detection, the microfluidic detection chip has the characteristics of fast detection speed, less consumption of samples and reagents, high throughput, functional integration and automated analysis. This article focuses on the research progress of silicon-based, polymer and paper-based immune microfluidic detection chips from the aspects of chip design, manufacturing process, surface modification, etc., and analyzes the advantages and disadvantages of each chip. At the same time, the current challenges and opportunities of the immunological microfluidic detection chip are discussed, and the future development trend of this technology is prospected.

Key words： immunology; microfluidic chip; foodborne pathogens; food safety

Cite this article

LI Bin , LIU Cheng , TIAN Yachen , LIU Qing , LI Daixi , HUANG Xiaotian , LIU Tao , YANG Hao . Research progress of immunology-based microfluidic chip for rapid detection of pathogens[J]. Food and Fermentation Industries, 2022 , 48(12) : 316 -323 . DOI: 10.13995/j.cnki.11-1802/ts.029394

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