Research progress on purine content and the reduction methods of purine in meat

  • PENG Songlin ,
  • ZENG Zhiguo ,
  • ZHANG Tao ,
  • SHANG Yongbiao
Expand
  • 1(College of Food Science, Southwest University, Chongqing 400715, China)
    2(Fengdu County Service Center for Beef Cattle Industry Development, Chongqing 408200, China)
    3(Laboratory of Quality and Safety Risk Assessment for Agro- Products on Storage and Preservation(Chongqing),Ministry of Agriculture, Chongqing 400715, China)
    4(Chongqing Engineering Research Center for Special Foods, Chongqing 400715, China)

Received date: 2021-07-30

  Revised date: 2021-12-14

  Online published: 2022-10-17

Abstract

Purine, an important nitrogen-containing base in organisms, is metabolized into uric acid in the body. When ingestion too much purine or purine metabolism disorder, it will lead to hyperuricemia, increase the incidence of gout and harm to human health. Meat is an important source of purine intake, and high purine content in meat can significantly affect blood uric acid levels in the body. In this paper, the relationship between purine and gout, the methods of purine pretreatment, detection conditions, the content of purine and the methods of purine reduction were reviewed so as to provide reference for the further study of purine. It could also provide scientific guidance for consumers to choose meat products and how to reduce the content of purine.

Cite this article

PENG Songlin , ZENG Zhiguo , ZHANG Tao , SHANG Yongbiao . Research progress on purine content and the reduction methods of purine in meat[J]. Food and Fermentation Industries, 2022 , 48(18) : 314 -321 . DOI: 10.13995/j.cnki.11-1802/ts.028851

References

[1] 林洪, 曲欣.食品中嘌呤含量分布的研究进展[J].食品安全质量检测学报, 2012, 3(5):373-378.
LIN H, QU X.The research progress of purine distribution in food[J].Journal of Food Safety and Quality, 2012, 3(5):373-378.
[2] DÖLLE C, RACK J G M, ZIEGLER M.NAD and ADP-ribose metabolism in mitochondria[J].The FEBS Journal, 2013, 280(15):3 530-3 541.
[3] MAIUOLO J, OPPEDISANO F, GRATTERI S, et al.Regulation of uric acid metabolism and excretion[J].International Journal of Cardiology, 2016, 213:8-14.
[4] 于康, 李融融, 李春微, 等.WS/T 560—2017,高尿酸血症与痛风患者膳食指导 [M].北京:国家标准出版社, 2017.
YU K, LI R R, LI C W, et al.WS/T 560—2017,Dietary Guide for Hyperuricemia and Gout Patients[M].Beijing:National Standards Publishing House, 2017.
[5] AIHEMAITIJIANG S, ZHANG Y Q, ZHANG L, et al.The association between purine-rich food intake and hyperuricemia:A cross-sectional study in Chinese adult residents[J].Nutrients, 2020, 12(12):3 835.
[6] 宋洁, 刘晓飞, 王薇, 等.大豆嘌呤的研究进展[J].食品工业, 2019, 40(1):295-298.
SONG J, LIU X F, WANG W, et al.Research progress of soybean purine[J].The Food Industry, 2019, 40(1):295-298.
[7] 曲欣. 水产品中嘌呤含量分布及其在贮藏加工中变化规律的研究[D].青岛:中国海洋大学, 2013.
QU X.Study on the contents and change rules during storage and processing of purines in aquatic foods[D].Qingdao:Ocean University of China, 2013.
[8] 蔡路昀, 张滋慧, 曹爱玲, 等.食品中的嘌呤含量分布及在贮藏加工中变化研究进展[J].食品科学, 2018, 39(19):260-265.
CAI L Y, ZHANG Z H, CAO A L, et al.Advances in research on purine distribution in foods and its changes during storage and processing[J].Food Science, 2018, 39(19):260-265.
[9] 荣胜忠, 邹立娜, 崔新宇, 等.中国居民膳食嘌呤摄入量评估[J].营养学报, 2015, 37(3):226-228;234.
RONG S Z, ZOU L N, CUI X Y, et al.Assessment of dietary purine intake in Chinese residents[J].Acta Nutrimenta Sinica, 2015, 37(3):226-228;234.
[10] MAJOR T J, TOPLESS R K, DALBETH N, et al.Evaluation of the diet wide contribution to serum urate levels:Meta-analysis of population based cohorts[J].BMJ (Clinical Research Ed.), 2018, 363:k3951.
[11] 徐李华. 食品中嘌呤含量与高尿酸血症关系的研究进展[J].中国城乡企业卫生, 2020, 35(1):26-28.
XU L H.Research progress on the association between purine content in food and hyperuricemia[J].Chinese Journal of Urban and Rural Enterprise Hygiene, 2020, 35(1):26-28.
[12] 王新宴, 凌云, 储晓刚, 等.肉制品中四种嘌呤含量在水煮过程中的变化[J].食品科学, 2008, 29(7):67-69.
WANG X Y, LING Y, CHU X G,et al.Effects of boil processing on content of four kinds of purines in meat products [J].Food Science, 2008, 29(7):67-69.
[13] 骆婕怡, 汪薇, 自卫东, 等.猪肉汤中嘌呤含量的研究[C].广东省食品学会年会论文集.广州:广东省食品学会,2013:82-85.
LUO J Y, WANG W, ZI W D,et.al.Change of purines content in pork broth[C].Proceedings of the annual meeting of Guangdong food society.Guangzhou:Guangdong food society,2013:82-85
[14] 冯晓晶. 嘌呤及其代谢产物尿酸检测方法研究和应用[D].太原:山西医科大学, 2011.
FENG X J.Methods study for determination and application of purine and uric acid part Ⅰ methods study for determination of total amount of purine in food by diazotization-xanthine oxidase-HPLC[D].Taiyuan:Shanxi Medical University, 2011.
[15] 李婷婷, 任丽琨, 王当丰, 等.食品中嘌呤含量分布及其高效液相色谱检测研究进展[J].现代食品科技, 2018, 34(5):257-266.
LI T T, REN L K, WANG D F, et al.Purine content distribution in foods and purine determination by HPLC:A review[J].Modern Food Science and Technology, 2018, 34(5):257-266.
[16] LOU S N, CHEN H H, HSU P Y, et al.Changes in purine content of tilapia surimi products during processing[J].Fisheries Science, 2005, 71(4):889-895.
[17] FAN H, YANG F Q, LI S P.Determination of purine and pyrimidine bases in natural and cultured Cordyceps using optimum acid hydrolysis followed by high performance liquid chromatography[J].Journal of Pharmaceutical and Biomedical Analysis, 2007, 45(1):141-144.
[18] 张静. 常见食品中嘌呤类组分及其在加工贮藏中的变化规律研究[D].杭州:浙江工业大学, 2020.
ZHANG J.Study on purine components in common foods and the change rule during storage and processing[D].Hangzhou:Zhejiang University of Technology, 2020.
[19] 任丽琨. 基于HPLC的嘌呤碱基检测方法的建立及海水鱼嘌呤脱除探究[D].锦州:渤海大学, 2019.
REN L K.Study on the detection and removal of purine bases in marine fishes based on HPLC [D].Jinzhou:Bohai University, 2019.
[20] 张滋慧. 水产品中嘌呤含量的测定及脱嘌呤方法研究[D].锦州:渤海大学, 2019.
ZHANG Z H.Study on the purine content of aquatic products and purine removing method [D].Jinzhou:Bohai University, 2019.
[21] 杨海斌. 各种肉类食物中嘌呤类物质的检测[D].太原:山西医科大学, 2012.
YANG H B.Detection of purine substances in various meat foods[D].Taiyuan:Shanxi Medical University, 2012.
[22] 王静莹. 青海特色肉类中尿酸和嘌呤快速检测技术研究[D].西宁:青海师范大学, 2018.
WANG J Y.Study on rapid detection technology of uric acid and purine in meat of Qinghai [D].Xining:Qinghai Normal University, 2018.
[23] 吕兵兵. 不同储藏条件及烹制方法对带鱼嘌呤含量的影响研究[D].杭州:浙江大学, 2013.
LYU B B.Effctes of preserving and cooking on the content of purine in Trichiurus haumela[D].Hangzhou:Zhejiang University, 2013.
[24] 方妍, 谢定源, 丁璐, 等.优化高效液相色谱法测定鸡肉及鸡汤中嘌呤含量[J].中国调味品, 2020, 45(12):115-123.
FANG Y, XIE D Y, DING L,et al.Optimization of high performance liquid chromatography for detecting purine content in chicken and chicken soup [J].China Condiment, 2020, 45(12):115-123.
[25] 李婷婷, 任丽琨, 王当丰, 等.大蒜粉处理对海鲈鱼嘌呤含量的影响[J].中国食品学报, 2020, 20(11):107-114.
LI T T, REN L K, WANG D F, et al.Effect of garlic powder on purine content in Perca fluviatilis[J].Journal of Chinese Institute of Food Science and Technology, 2020, 20(11):107-114.
[26] TAKAYANAGI F, FUKUUCHI T, YAMAOKA N, et al.Measurement of the total purine contents and free nucleosides, nucleotides, and purine bases composition in Japanese anchovies (Engraulis japonicus) using high-performance liquid chromatography with UV detection[J].Nucleosides, Nucleotides & Nucleic Acids, 2020, 39(10-12):1 458-1 464.
[27] LI T T, REN L K, WANG D F, et al.Effect of allicin and its mechanism of action in purine removal in turbot[J].Journal of Food Science, 2020, 85(10):3 562-3 569.
[28] RONG S Z, ZOU L N, ZHANG Y N, et al.Determination of purine contents in different parts of pork and beef by high performance liquid chromatography[J].Food Chemistry, 2015, 170:303-307.
[29] KANEKO K, TAKAYANAGI F, FUKUUCHI T, et al.Determination of total purine and purine base content of 80 food products to aid nutritional therapy for gout and hyperuricemia[J].Nucleosides, Nucleotides & Nucleic Acids, 2020, 39(10-12):1 449-1 457.
[30] SABOLOVÁ M, KULMA M, KOUŘIMSKÁ L.Sex-dependent differences in purine and uric acid contents of selected edible insects[J].Journal of Food Composition and Analysis, 2021, 96:103746.
[31] 杨海斌, 张加玲, 刘桂英, 等.鸡鸭不同组织脏器中嘌呤和尿酸的含量及其分布研究[J].营养学报, 2013, 35(5):505-507.
YANG H B, ZHANG J L, LIU G Y, et al.Study on the contents and distribution of purines and uric acid in different tissues of chickens and ducks[J].Acta Nutrimenta Sinica, 2013, 35(5):505-507.
[32] QU X, SUI J X, MI N S, et al.Determination of four different purines and their content change in seafood by high-performance liquid chromatography[J].Journal of the Science of Food and Agriculture, 2017, 97(2):520-525.
[33] 凌云, 王新宴, 雍炜, 等.高效液相色谱法检测肉类食品中4种嘌呤碱[J].分析化学, 2008, 36(6):724-728.
LING Y, WANG X Y YONG W, et al.Deteminaton of four purines in meat by high performance liquid chromatography[J].Chinese Journal of Analytical Chemistry, 2008, 36(6):724-728.
[34] 程庆红. 海鲜食品中嘌呤类物质的提取与测定[D].长春:吉林大学, 2008.
CHENG Q H.Extraction and determination of purines in seafood [D].Changchun:Jilin University, 2008.
[35] MARKELJ J, ZUPANČIČ T, PIHLAR B.Optimization of high performance liquid chromatography method for simultaneous determination of some purine and pyrimidine bases[J].Acta Chimica Slovenica, 2016, 63(1):8-17.
[36] GUO X Y, WANG X Y, HUANG D W, et al.Method study on determination of total purine content in fish meat by diazotization reaction combined with SERS[J].LWT 2020, 123:109027.
[37] ZHANG Y Q, CHEN C, CHOI H, et al.Purine-rich foods intake and recurrent gout attacks[J].Annals of the Rheumatic Diseases, 2012, 71(9):1 448-1 453.
[38] 潘洪志, 荣胜忠, 邹立娜, 等.中国常见动物性食品中嘌呤的含量[J].营养学报, 2012, 34(1):74-78.
PAN H Z, RONG S Z, ZOU L N, et al.The contents of purine in common animal foods in China [J].Acta Nutrimenta Sinica, 2012, 34(1):74-78.
[39] ZHENG M, HUANG Y Z, JI J X, et al.Effects of breeds, tissues and genders on purine contents in pork and the relationships between purine content and other meat quality traits[J].Meat Science, 2018, 143:81-86.
[40] KANEKO K, AOYAGI Y, FUKUUCHI T, et al.Total purine and purine base content of common foodstuffs for facilitating nutritional therapy for gout and hyperuricemia[J].Biological & Pharmaceutical Bulletin, 2014, 37(5):709-721.
[41] 左俊英. 菌菇火锅底汤熬煮过程营养及安全性研究[D].扬州:扬州大学, 2013.
ZUO J Y.Study on nutrition and safety of mushroom hot pot soup during boiling[D].Yangzhou:Yangzhou University, 2013.
[42] 荣胜忠, 邹立娜, 王国栋, 等.涮火锅过程中肉、虾和汤中嘌呤含量变化研究[J].卫生研究, 2012, 41(6):1 014- 1016.
RONG S Z, ZOU L N, WANG G D, et al.Changes of purine content in meat, shrimp and soup during hot pot rinsing[J].Journal of Hygiene Research, 2012, 41(6):1 014-1 016.
[43] 刘建林, 孙学颖, 李敬超, 等.不同发酵剂对发酵羊肉干中嘌呤形成的影响[J].食品科技, 2020, 45(6):116-121.
LIU J L, SUN X Y, LI J C, et al.Inhibition of starter cultures on purine formation in mutton jerky[J].Food Science and Technology, 2020, 45(6):116-121.
[44] TAKAYANAGI F, FUKUUCHI T, YAMAOKA N, et al.The observed variation in the purine composition of food after soaking in sake lees[J].Nucleosides, Nucleotides & Nucleic Acids, 2018, 37(6):348-352.
[45] ZHANG Y F, WANG G, JIN Y F, et al.Effects of high hydrostatic pressure processing on purine, taurine, cholesterol, antioxidant micronutrients and antioxidant activity of squid (Todarodes pacificus) muscles[J].Food Control, 2016, 60:189-195.
[46] 孙宏, 李婷婷, 宋敏杰, 等.预制调理低嘌呤大菱鲆鱼片的制备及品质研究[J].食品工业科技, 2021, 42(2):58-62;69.
SUN H, LI T T,SONG M J, et al.Preparation and quality of pre-conditioned low purine turbot fillet[J].Science and Technology of Food Industry, 2021, 42(2):58-62;69.
[47] LI T T, REN L K, WANG D F, et al.Optimization of extraction conditions and determination of purine content in marine fish during boiling[J].PeerJ, 2019, 7:e6690.
[48] ZHANG R, GAO S J, ZHU C Y, et al.Characterization of a novel alkaline Arxula adeninivorans urate oxidase expressed in Escherichia coli and its application in reducing uric acid content of food[J].Food Chemistry, 2019, 293:254-262.
[49] 李学鹏, 谢晓霞, 朱文慧, 等.食品中鲜味物质及鲜味肽的研究进展[J].食品工业科技, 2018, 39(22):319-327.
LI X P, XIE X X, ZHU W H, et al.Research progress of umami substances and umami peptides in food[J].Science and Technology of Food Industry, 2018, 39(22):319-327.
[50] 杜超. 反复炖煮对鸡肉和鸡汤风味品质的影响[D].锦州:渤海大学, 2020.
DU C.Effect of repeated stewing on the flavor formation of chicken and chicken broth[D].Jinzhou:Bohai University, 2020.
Outlines

/