Food and Fermentation Industries >

2022 , Vol. 48 >Issue 23: 156 - 164

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.029698

Development and release behavior of dihydromyricetin-loaded Pickering emulsions stabilized by dialdehyde cellulose nanocrystals

  • GE Liming ,
  • XU Jinfang ,
  • MU Changdao ,
  • LI Defu
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  • (School of Chemical Engineering, Sichuan University, Chengdu 610065, China)

Received date: 2021-10-14

  Revised date: 2021-10-29

  Online published: 2023-01-05

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Abstract

Cellulose nanocrystalline (CNC) was prepared by the sulfuric acid hydrolysis of α-cellulose. Then the ortho-hydroxyl group of CNC was specifically oxidized to the aldehyde group by sodium periodate to obtain dialdehyde cellulose nanocrystalline (DCNC). Dihydromyricetin-loaded Pickering emulsions were prepared using CNC and DCNC suspension as the aqueous phase and soybean oil as the oil phase. The results indicated that DCNC with controllable aldehyde group content could be prepared by adjusting the dosage of sodium periodate. Pickering emulsion prepared by the optimal parameters (10.0 g/L of DCNC3, 0.4 of the oil/water ratio, 50 mmol/L of salt ions) emulsified by the combination process of ultrasonic and homogeneous were very stable during storage and centrifugation. The reduced particle size and the surface negative charge of CNC by sodium periodate oxidation made a great contribution to significantly enhancing the stability of Pickering emulsion. The release rate of dihydromyricetin from DCNC stabilized Pickering emulsion was gradually slowed down with the increasing aldehyde content of DCNC. It was found that the sustained release of dihydromyricetin from Pickering emulsion conforms to the Weibull distribution model. The in vitro dihydromyricetin release mechanism from Pickering emulsion was based on dissolution and diffusion. Overall, the stability and sustained-release behavior of DCNC stabilized Pickering emulsion can be effectively adjusted by controlling the oxidation degree of CNC.

Key words： Pickering emulsion; cellulose nanocrystalline; sodium periodate oxidation; dihydromyricetin; sustained-release behaviour

Cite this article

GE Liming , XU Jinfang , MU Changdao , LI Defu . Development and release behavior of dihydromyricetin-loaded Pickering emulsions stabilized by dialdehyde cellulose nanocrystals[J]. Food and Fermentation Industries, 2022 , 48(23) : 156 -164 . DOI: 10.13995/j.cnki.11-1802/ts.029698

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