Bifidobacterium promotes the growth of Faecalibacterium prausnitzii in inulin

  • GAO Wenyu ,
  • XIAO Yue ,
  • WANG Hongchao ,
  • ZHU Jinlin ,
  • LU Wenwei
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  • 1(School of Food Science and Technology, Jiangnan University, Wuxi 214122, China)
    2(National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China)

Received date: 2023-03-02

  Revised date: 2023-03-17

  Online published: 2024-02-27

Abstract

Faecalibacterium prausnitzii is a commensal gut bacterium that accounts for about 5% of total bacteria. It is the main butyrate-producing bacterium and plays a vital role in maintaining human health. It has decreased greatly in patients with intestinal disorders and metabolic diseases. However, this species is extremely sensitive to oxygen, which limits the application as a probiotic. Thus, it is pressing to find an alternative strategy to improve its growth. It has established a co-culture system between F. prausnitzii and Bifidobacterium, the results demonstrated that Bifidobacterium could greatly improve the growth of F. prausnitzii and increase the content of butyrate. The 16S rRNA sequencing discovered that Bifidobacterium and inulin can increased the abundance of F. prausnitzii in fecal flora. It has provided a theoretical basis for the proliferation of F. prausnitzii in human intestines.

Cite this article

GAO Wenyu , XIAO Yue , WANG Hongchao , ZHU Jinlin , LU Wenwei . Bifidobacterium promotes the growth of Faecalibacterium prausnitzii in inulin[J]. Food and Fermentation Industries, 2024 , 50(2) : 85 -92 . DOI: 10.13995/j.cnki.11-1802/ts.035341

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