Zeaxanthin is a carotenoid, which has certain applications in many fields.In this study, a zeaxanthin-yielding strain was obtained based on a previous construction of Saccharomyces cerevisiae with lipid engineering. Further optimization of the feeding resource, feeding time and feeding mode, the yield of zeaxanthin was increased to 47.7 mg/L when feeding glucose after 48 h under the exponential feeding mode in 5 L fermentor.To sum up, In this study, a recombinant strain with high yield of zeaxanthin was constructed and its fermentation validation was carried out.The research results provided the basis and improvement direction for subsequent fermentation optimization.
ZHAO Chongyi
,
ZHOU Jingwen
,
XU Sha
. Metabolic engineering of Saccharomyces cerevisiae for zeaxanthin synthesis[J]. Food and Fermentation Industries, 2024
, 50(5)
: 1
-6
.
DOI: 10.13995/j.cnki.11-1802/ts.035321
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