Research progress in screening of acetone, butanol and ethanol producing strains with high butanol-tolerant

  • DING Huanhuan ,
  • HUANG Siyi ,
  • ZHOU Qiuxiang ,
  • BU Jing ,
  • SHI Chaoyue ,
  • LI Hanguang
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  • 1(Institute of Applied Microbiology/College of Biological Science and Engineering, Jiangxi Agricultural University, Nanchang 330045, China)
    2(Affiliated Hospital of Jiangxi Agricultural University, Nanchang 330045, China)

Received date: 2023-05-08

  Revised date: 2023-06-01

  Online published: 2024-04-17

Abstract

The fossil fuels as a mainly traditional non-renewable energy sources perform an important role in promoting economic development.However, a serious threat to the ecological environment occurred due to theirs application.Therefore, the research and application of new renewable energy has become an important direction in both industrial and academic worlds.Biobutanol has attracted renew interest in the field of biomass energy because of its environmental friendly and renewable advantages.However, butanol toxicity to the current producing microorganisms limits its accumulation in the fermentation broth, and for this reason the acetone, butanol, and ethanol (ABE) fermentation is of low production, yield and conversion efficiency.Therefore, improvement of butanol tolerance of butanol producing strains is one of the promising ways to enhance the economically competitive of ABE fermentation.This review summarized the principles of different methods, such as various mutagenesis breeding, adaptive domestication strategies, and synthetic biology, to improve butanol tolerance of butanol-producing strains.And we also reviewed its domestic and international research progress.Furthermore, we also discussed the challenges, advantages and disadvantages of those methods in the applications.The results from this review will provide some theoretical and practical references for screening of some higher butanol tolerance of microorganisms.

Cite this article

DING Huanhuan , HUANG Siyi , ZHOU Qiuxiang , BU Jing , SHI Chaoyue , LI Hanguang . Research progress in screening of acetone, butanol and ethanol producing strains with high butanol-tolerant[J]. Food and Fermentation Industries, 2024 , 50(6) : 300 -306 . DOI: 10.13995/j.cnki.11-1802/ts.036058

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