Recent advances on the synthesis of biobutanol by non-solvent microorganisms

  • YU Leyong ,
  • YU Hairui ,
  • ZHAO Youzhi ,
  • WANG Lihua ,
  • YUAN Ziyi ,
  • ZHUANG Wenjing
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  • 1(Key Laboratory of Biochemistry and Molecular Biology in Universities of Shandong (Weifang University), Weifang Key Laboratory of Coho Salmon Culturing Facility Engineering, Institute of Modern Facility Fisheries, College of Biology and Oceanography, Weifang University, Weifang 261061, China)
    2(Weifang Centre for the Promotion of Scientific and Technological Innovation, Weifang 261000, China)

Received date: 2023-06-23

  Revised date: 2023-08-01

  Online published: 2024-08-02

Abstract

As an important bulk chemical and potential biofuel, butanol has a wide range of applications in many fields.The depletion of fossil fuels and the progress of synthetic biotechnology have renewed interest in the production of biobutanol.Solvent-producing Clostridium is commonly used to produce butanol through traditional acetone-butanol-ethanol (ABE) fermentation.However, its relatively slow growth rate, low butanol tolerance and production efficiency hinder its further application.Recently, researchers have studied some other promising industrial hosts as the chassis to produce butanol, including Escherichia coli, Saccharomyces cerevisiae, C.tyrobutyricum and so on.This review comprehensively summarizes the advantages and challenges of different non-solvent strains for the production of butanol, in order to better determine the ideal non-solvent host for the production of butanol.In addition, a strategy to further increase the production of butanol was also proposed.

Cite this article

YU Leyong , YU Hairui , ZHAO Youzhi , WANG Lihua , YUAN Ziyi , ZHUANG Wenjing . Recent advances on the synthesis of biobutanol by non-solvent microorganisms[J]. Food and Fermentation Industries, 2024 , 50(13) : 323 -330 . DOI: 10.13995/j.cnki.11-1802/ts.036544

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