Food and Fermentation Industries >

2024 , Vol. 50 >Issue 14: 142 - 150

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.036839

Comparative genomics analysis of Bifidobacterium pseudocatenulatum

  • LU Jingda ,
  • YANG Rui ,
  • ZHONG Gang ,
  • GONG Yanchun ,
  • ZHOU Junhong ,
  • ZHANG Yixin ,
  • XU Weina ,
  • ZHONG Zhi
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  • 1(Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, China)
    2(Inner Mongolia Agriculture and Animal Husbandry Technology Popularization Centre, Hohhot 010010, China)

Received date: 2023-07-20

  Revised date: 2023-08-28

  Online published: 2024-08-02

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Abstract

In order to analyze the differences in functional genes of Bifidobacterium pseudocatenulatum.Comparative genomics analysis was performed on 104 strains of Bifidobacterium pseudocatenulatum isolated from China, Japan and America.The results showed that the number of coding sequences of Japanese isolates were significantly higher than Chinese and American isolates in genome level (P<0.01).Phylogenetic tree based on core gene and average nucleotide identity clustering heat map showed that strains isolated from the same country were more similar.The results of functional gene annotation further showed that the isolation could affect the functional genes distribution of strains.The annotation of carbohydrate active enzymes revealed that 15 carbohydrate active enzymes had regional differences.The number of antibiotic resistance genes and adhesion virulence factors carried by Chinese isolates were more abundant than Japanese isolates by the annotation of antibiotic resistance genes database and virulence factors database.The number of Replication\recombination\repair and phage associated mobile genetic elements carried by the Chinese and Japanese isolates were different from American isolates.In this study, it was found that the location of strains will affect the functional genes of Bifidobacterium pseudocatenulatum, and Bifidobacterium pseudocatenulatum in different locations have different functional genes.This study provides theoretical basis for the analysis of the functional differences of Bifidobacterium pseudocatenulatum.

Key words： Bifidobacterium pseudocatenulatum; comparative genomics; carbohydrate active enzymes; antibiotics resistance genes; virulence factor

Cite this article

LU Jingda , YANG Rui , ZHONG Gang , GONG Yanchun , ZHOU Junhong , ZHANG Yixin , XU Weina , ZHONG Zhi . Comparative genomics analysis of Bifidobacterium pseudocatenulatum[J]. Food and Fermentation Industries, 2024 , 50(14) : 142 -150 . DOI: 10.13995/j.cnki.11-1802/ts.036839

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