Food and Fermentation Industries >

2024 , Vol. 50 >Issue 15: 409 - 416

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.037608

Progress in the manufacture of intelligent bioreactor equipment

  • LIU Keyi ,
  • WANG Junqing ,
  • FU Kai ,
  • LI Feng ,
  • WANG Ruiming ,
  • LI Piwu
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  • 1(College of Bioengineering, Qilu University of Technology(Shandong Academy of Sciences), Jinan 250353, China)
    2(State Key Laboratory of Biobased Material and Green Papermaking, Jinan 250353, China)
    3(Shandong Shendong intelligent equipment Co. Ltd., Dezhou 253000, China)

Received date: 2023-10-10

  Revised date: 2023-10-24

  Online published: 2024-08-21

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Abstract

The bioreactor serves as the fundamental equipment in the biomedicine and biotechnology industry, with the global market witnessing continuous growth year after year.It is poised to become a pivotal driver of expansion within the realm of equipment manufacturing.With the rapid advancements in synthetic biology and artificial intelligence technology, high-throughput and miniaturized bioreactors have been implemented for process development and optimization, while large-scale bioreactors are evolving towards low energy consumption and intelligent operation.The intricate flow field structure within a bioreactor poses a significant challenge to scaling up biological processes, necessitating comprehensive research on factors such as mixing, mass transfer, shear stress, among others.To enhance the, techniques like artificial intelligence and machine learning are indispensable for data acquisition and optimization purposes.In the future, highly integrated intelligent bioreactors expertise from various domains including biotechnology, information technology, and control technology will find extensive applications across multiple fields.

Key words： bioreactor; computational fluid dynamics; sensor; intelligentize; machine learning

Cite this article

LIU Keyi , WANG Junqing , FU Kai , LI Feng , WANG Ruiming , LI Piwu . Progress in the manufacture of intelligent bioreactor equipment[J]. Food and Fermentation Industries, 2024 , 50(15) : 409 -416 . DOI: 10.13995/j.cnki.11-1802/ts.037608

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