Research progress on the regulation mechanisms of dietary fiber on bile acid metabolism through the intestine

  • LI Jingwen ,
  • LIU Chunxia ,
  • LI Shanshan ,
  • FANG Zhengfeng ,
  • CHEN Hong
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  • (College of Food Science, Sichuan Agricultural University, Ya’an 625014, China)

Received date: 2024-05-21

  Revised date: 2024-07-13

  Online published: 2025-04-29

Abstract

Dietary fiber can regulate the level of bile acids in the body, and bile acids are reabsorbed, metabolized and excreted through the intestinal tract.The biological activity of dietary fiber is also closely related to the intestinal tract.Although in vitro and in vivo experiments in recent years have proved the interaction between dietary fiber and bile acids, the regulatory mechanism between the two is still poorly understood.This report summarized the mechanisms of dietary fiber binding bile acids in the small intestine, regulating the expression of bile acid receptors and the structural changes of gut microbiota.The report provided new ideas for the subsequent research on the development of dietary fiber and the mechanism of regulating bile acids, and formulated new targeted regulation strategies.It provides new ideas to further investigate the mechanism of action between bile acids and dietary fibers, new references for precise regulation of bile acid metabolism by dietary fibers in vivo, and new strategies for targeted regulation.

Cite this article

LI Jingwen , LIU Chunxia , LI Shanshan , FANG Zhengfeng , CHEN Hong . Research progress on the regulation mechanisms of dietary fiber on bile acid metabolism through the intestine[J]. Food and Fermentation Industries, 2025 , 51(7) : 351 -359 . DOI: 10.13995/j.cnki.11-1802/ts.039898

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