[1] CAI R, ZHOU C H, TANG R S, et al.Current insights on gut microbiome and chronic urticaria:Progress in the pathogenesis and opportunities for novel therapeutic approaches[J].Gut Microbes, 2024, 16(1):2382774.
[2] AZIZ Q, DORÉ J, EMMANUEL A, et al.Gut microbiota and gastrointestinal health:Current concepts and future directions[J].Neurogastroenterology & Motility, 2013, 25(1):4-15.
[3] GOU H Z, ZHANG Y L, REN L F, et al.How do intestinal probiotics restore the intestinal barrier?[J].Frontiers in Microbiology, 2022, 13:929346.
[4] LATIF A, SHEHZAD A, NIAZI S, et al.Probiotics:Mechanism of action, health benefits and their application in food industries[J].Frontiers in Microbiology, 2023, 14:1216674.
[5] 赵丽霞, 刘文俊.母乳中乳酸菌多样性及益生菌开发利用研究进展[J].食品与生物技术学报,2024, 43(4):25-34.
ZHAO L X, LIU W J.Research progress on diversity of lactic acid bacteria and probiotics exploitation in breast milk[J].Journal of Food Science and Biotechnology,2024, 43(4):25-34.
[6] 尹春媚. 母乳源乳酸菌的筛选、鉴定及其益生特性研究[D].长春:吉林农业大学, 2020.
YIN C M.Screening, identification, and probiotic properties of lactic acid bacteria derived from breast milk[D].Changchun:Jilin Agricultural University, 2020.
[7] 董学艳, 姜铁民, 刘继超, 等.母乳中乳酸菌的研究进展[J].食品工业科技,2016, 37(19):391-395.
DONG X Y, JIANG T M, LIU J C, et al.Research progress in lactic acid bacteria in breast milk[J].Science and Technology of Food Industry, 2016, 37(19):391-395.
[8] 高盛, 乔宇, 张宇微, 等.人母乳源乳酸菌的筛选、鉴定及益生活性的初步研究[J].食品工业科技, 2017, 38(10):205-210.
GAO S, QIAO Y, ZHANG Y W, et al.Isolation, identification and probiotic characterization of lactic acid bacteria in human breast milk[J].Science and Technology of Food Industry, 2017, 38(10):205-210.
[9] 李双祁. 母乳来源益生菌的筛选和益生作用研究[D].广州:广东工业大学, 2022.
LI S Q.Study on the screening and probiotic effect of human milk derived probiotics[D].Guangzhou:Guangdong University of Technology, 2022.
[10] 胡鹏钰, 于俊娟, 王鹏, 等.母乳来源益生菌的筛选及潜在益生特性研究[J].食品与发酵工业, 2021, 47(14):190-195.
HU P Y, YU J J, WANG P, et al.Screening of probiotics from breast milk and its potential probiotic characteristics[J].Food and Fermentation Industries, 2021, 47(14):190-195.
[11] 国笑情, 武岳, 李瑜, 等.新疆地区母乳中乳酸菌的分离鉴定及潜在益生菌的筛选[J].食品与发酵工业, 2023, 49(18):275-281.
GUO X Q, WU Y, LI Y, et al.Isolation and identification of lactic acid bacteria from breast milk in Xinjiang and screening of potential probiotics[J].Food and Fermentation Industries, 2023, 49(18):275-281.
[12] 丁梦帆. 母乳菌群构成及优势乳酸菌影响幼鼠肠黏膜免疫研究[D].无锡:江南大学, 2019.
DING M F.Composition of human milk microbiota and influence of dominant lactic acid bacteria on intestinal mucosal immunity in young rats[D].Wuxi:Jiangnan University, 2019.
[13] MARTÍN R, JIMÉNEZ E, HEILIG H, et al.Isolation of bifidobacteria from breast milk and assessment of the bifidobacterial population by PCR-denaturing gradient gel electrophoresis and quantitative real-time PCR[J].Applied and Environmental Microbiology, 2009, 75(4):965-969.
[14] 韩菲. 母乳中乳酸菌的分离鉴定及链球菌属新种的多相分类学研究[D].呼和浩特:内蒙古农业大学, 2022.
HAN F.Isolation and identification of lactic acid bacteria from human milk and polyphase taxonomic study of new species of Streptococcus[D].Hohhot:Inner Mongolia Agricultural University, 2022.
[15] KIM K J, KYUNG S, JIN H, et al.Lactic acid bacteria isolated from human breast milk improve colitis induced by 2,4,6-trinitrobenzene sulfonic acid by inhibiting NF-κB signaling in mice[J].Journal of Microbiology and Biotechnology, 2023, 33(8):1057-1065.
[16] LATUGA M S, STUEBE A, SEED P C.A review of the source and function of microbiota in breast milk[J].Seminars in Reproductive Medicine, 2014, 32(1):68-73.
[17] YANG L, SAKANDAR H A, SUN Z H, et al.Recent advances of intestinal microbiota transmission from mother to infant[J].Journal of Functional Foods, 2021, 87:104719.
[18] LYONS K E, RYAN C A, DEMPSEY E M, et al.Breast milk, a source of beneficial microbes and associated benefits for infant health[J].Nutrients, 2020, 12(4):1039.
[19] FRAGA M, PERELMUTER K, DELUCCHI L, et al.Vaginal lactic acid bacteria in the mare:Evaluation of the probiotic potential of native Lactobacillus spp.and Enterococcus spp.strains[J].Antonie Van Leeuwenhoek, 2008, 93(1):71-78.
[20] SHAZADI K, ARSHAD N.Evaluation of inhibitory and probiotic properties of lactic acid bacteria isolated from vaginal microflora[J].Folia Microbiologica, 2022, 67(3):427-445.
[21] 林永创, 李依米, 吴璐璐, 等.正常顺产婴儿出生6月内肠道菌群的发育特征[J].暨南大学学报(自然科学与医学版), 2022, 43(1):43-52.
LIN Y C, LI Y M, WU L L, et al.The development characteristics of intestinal flora of healthy infant within 6 months after vaginal delivery[J].Journal of Jinan University (Natural Science & Medicine Edition), 2022, 43(1):43-52.
[22] MASTROMARINO P, CAPOBIANCO D, MICCHELI A, et al.Administration of a multistrain probiotic product (VSL#3) to women in the perinatal period differentially affects breast milk beneficial microbiota in relation to mode of delivery[J].Pharmacological Research, 2015, 95-96:63-70.
[23] BI C L, ZHANG S J, SHEN Y Z, et al.Selenium plays an anti-inflammatory role by regulation NLRP3 inflammasome in Staphylococcus aureus-infected mouse mammary gland[J].Biological Trace Element Research, 2021, 199(2):604-610.
[24] CHEN X, LI P, LIU M, et al.Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation[J].Gut, 2020, 69(3):513-522.
[25] STINSON L F, SINDI A S M, CHEEMA A S, et al.The human milk microbiome:Who, what, when, where, why, and how?[J].Nutrition Reviews, 2021, 79(5):529-543.
[26] PEREZ P F, DORÉ J, LECLERC M, et al.Bacterial imprinting of the neonatal immune system:Lessons from maternal cells?[J].Pediatrics, 2007, 119(3):E724-E732.
[27] PANNARAJ P S, LI F, CERINI C, et al.Association between breast milk bacterial communities and establishment and development of the infant gut microbiome[J].JAMA Pediatrics, 2017, 171(7):647-654.
[28] NYANGAHU D D, JASPAN H B.Influence of maternal microbiota during pregnancy on infant immunity[J].Clinical and Experimental Immunology, 2019, 198(1):47-56.
[29] SARKAR A, YOO J Y, VALERIA OZORIO DUTRA S, et al.The association between early-life gut microbiota and long-term health and diseases[J].Journal of Clinical Medicine, 2021, 10(3):459.
[30] LI Y P, REN L, WANG Y Y, et al.The effect of breast milk microbiota on the composition of infant gut microbiota:A cohort study[J].Nutrients, 2022, 14(24):5397.
[31] ARRIETA M C, STIEMSMA L T, AMENYOGBE N, et al.The intestinal microbiome in early life:Health and disease[J].Frontiers in Immunology, 2014, 5:427.
[32] QI C, DING M F, LI S Q, et al.Sex-dependent modulation of immune development in mice by secretory IgA-coated Lactobacillus reuteri isolated from breast milk[J].Journal of Dairy Science, 2021, 104(4):3863-3875.
[33] YU R Q, MA Y Z, LUO Z C, et al.Maternal supplementation with Limosilactobacillus reuteri FN041 for preventing infants with atopic dermatitis:Study protocol for a randomized controlled trial[J].Frontiers in Microbiology, 2023, 14:1267448.
[34] ZHOU J B, XU G S, LI X Y, et al.Limosilactobacillus reuteri FN041 prevents atopic dermatitis in pup mice by remodeling the ileal microbiota and regulating gene expression in Peyer’s patches after vertical transmission[J].Frontiers in Nutrition, 2022, 9:987400.
[35] PASTOR-VILLAESCUSA B, HURTADO J A, GIL-CAMPOS M, et al.Effects of Lactobacillus fermentum CECT5716 Lc40 on infant growth and health:A randomised clinical trial in nursing women[J].Beneficial Microbes, 2020, 11(3):235-244.
[36] MALDONADO-LOBÓN J A, GIL-CAMPOS M, MALDONADO J, et al.Long-term safety of early consumption of Lactobacillus fermentum CECT5716:A 3-year follow-up of a randomized controlled trial[J].Pharmacological Research, 2015, 95-96:12-19.
[37] MALDONADO J, CAÑABATE F, SEMPERE L, et al.Human milk probiotic Lactobacillus fermentum CECT5716 reduces the incidence of gastrointestinal and upper respiratory tract infections in infants[J].Journal of Pediatric Gastroenterology and Nutrition, 2012, 54(1):55-61.
[38] MALDONADO J, GIL-CAMPOS M, MALDONADO-LOBÓN J A, et al.Evaluation of the safety, tolerance and efficacy of 1-year consumption of infant formula supplemented with Lactobacillus fermentum CECT5716 Lc40 or Bifidobacterium breve CECT7263:A randomized controlled trial[J].BMC Pediatrics, 2019, 19(1):361.
[39] LARA-VILLOSLADA F, SIERRA S, BOZA J, et al.Beneficial effects of consumption of a dairy product containing two probiotic strains, Lactobacillus coryniformis CECT5711 and Lactobacillus gasseri CECT5714 in healthy children[J].Nutricion Hospitalaria, 2007, 22(4):496-502.
[40] MARTÍNEZ-CAÑAVATE A, SIERRA S, LARA-VILLOSLADA F, et al.A probiotic dairy product containing L.gasseri CECT5714 and L.coryniformis CECT5711 induces immunological changes in children suffering from allergy[J].Pediatric Allergy and Immunology, 2009, 20(6):592-600.
[41] JANDHYALA S M, TALUKDAR R, SUBRAMANYAM C, et al.Role of the normal gut microbiota[J].World Journal of Gastroenterology, 2015, 21(29):8787-8803.
[42] LUBIN J B, GREEN J, MADDUX S, et al.Arresting microbiome development limits immune system maturation and resistance to infection in mice[J].Cell Host & Microbe, 2023, 31(4):554-570.e7.
[43] LIU Y, WANG J Q, WU C X.Modulation of gut microbiota and immune system by probiotics, pre-biotics, and post-biotics[J].Frontiers in Nutrition, 2022, 8:634897.
[44] BADAL V D, VACCARIELLO E D, MURRAY E R, et al.The gut microbiome, aging, and longevity:A systematic review[J].Nutrients, 2020, 12(12):3759.
[45] LIU A L, MA T, XU N, et al.Adjunctive probiotics alleviates asthmatic symptoms via modulating the gut microbiome and serum metabolome[J].Microbiology Spectrum, 2021, 9(2):e0085921.
[46] OLIVARES M, DÍAZ-ROPERO M P, GÓMEZ N, et al.Oral administration of two probiotic strains, Lactobacillus gasseri CECT5714 and Lactobacillus coryniformis CECT5711, enhances the intestinal function of healthy adults[J].International Journal of Food Microbiology, 2006, 107(2):104-111.
[47] ZHENG Y, YU Z J, ZHANG W Y, et al.Lactobacillus rhamnosus probio-M9 improves the quality of life in stressed adults by gut microbiota[J].Foods, 2021, 10(10):2384.
[48] ZHANG M, ZHENG Y, SUN Z, et al.Change in the gut microbiome and immunity by Lacticaseibacillus rhamnosus probio-M9[J].Microbiology Spectrum, 2023, 11(2):e0360922.
[49] MALDONADO J, LARA-VILLOSLADA F, SIERRA S, et al.Safety and tolerance of the human milk probiotic strain Lactobacillus salivarius CECT5713 in 6-month-old children[J].Nutrition, 2010, 26(11-12):1082-1087.
[50] SIERRA S, LARA-VILLOSLADA F, SEMPERE L, et al.Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults[J].Anaerobe, 2010, 16(3):195-200.
[51] LI Y L, SHI X, MA T, et al.Bifidobacterium lactis Probio-M8 relieved acute respiratory tract infections in children possibly by modulating the gut microbes and metabolites[J].Journal of Functional Foods, 2024, 115:106111.
[52] ZHAO F Y, GUO Z G, KWOK L Y, et al.Bifidobacterium lactis Probio-M8 improves bone metabolism in patients with postmenopausal osteoporosis, possibly by modulating the gut microbiota[J].European Journal of Nutrition, 2023, 62(2):965-976.
[53] 陈卫. iLABdb数据库:乳酸菌研究和产业开发的里程碑[J].科学通报,2024, 69(3):327-329.
CHEN W.iLABdb:A milestone database for lactic acid bacteria research and industrial development[J].Chinese Science Bulletin, 2024, 69(3):327-329.
[54] 张和平, 高广琦.基于人工智能的益生乳酸菌精准筛选及产业化关键技术[J].中国食品学报,2023, 23(6):1-7.
ZHANG H P, GAO G Q.The key technologies of precise isolation and industrialization of probiotic lactic acid bacteria based on artificial intelligence[J].Journal of Chinese Institute Food Science and Technology, 2023, 23(6):1-7.
[55] 陈历俊, 刘璐, 赵军英, 等.一种母乳源植物乳杆菌HM-P2及其应用:CN115491329A[P].北京, 2023-06-16.
CHEN L J, LIU L, ZHAO J Y, et al.Breast milk-derived Lactiplantibacillus plantarum HM-P2 and its application:CN115491329A[P].Beijing, 2023-06-16.
[56] 陈历俊, 季亚栋, 李先平, 等.一株罗伊氏乳杆菌及其应用:CN202211014259.2[P].北京, 2024-04-09.
CHEN L J, JI Y D, LI X P, et al.A strain of Lactobacillus reuteri and its application:CN202211014259.2[P].Beijing, 2024-04-09.
[57] 陈历俊, 刘璐, 尹春媚, 等.一种母乳源植物乳杆菌及其应用:CN202010535484.5[P].北京, 2021-12-14.
CHEN L J, LIU L, YIN C M, et al.A breast milk-derived Lactiplantibacillus plantarum and its application:CN202010535484.5[P].Beijing, 2021-12-14.
[58] 陈历俊, 刘璐, 李先平, 等.格氏乳杆菌B1-26及其应用:CN202311695608.6[P].北京, 2024-01-12.
CHEN L J, LIU L, LI X P, et al.Lactobacillus gasseri B1-26 and its application:CN202311695608.6[P].Beijing, 2024-01-12.
[59] 姜铁民, 陈历俊, 宋家乐, 等.一株具有改善多囊卵巢综合征激素和神经递质水平的植物乳植杆菌B5及其应用:CN202311386417.1[P].广西壮族自治区, 2024-03-08.
JIANG T M, CHEN L J, SONG J L, et al.Lactiplantibacillus plantarum B5 capable of improving hormone and neurotransmitter levels in polycystic ovary syndrome and its application:CN202311386417.1[P].Guangxi Zhuang Autonomous Region, 2024-03-08.
[60] 康文丽, 汪家琦, 周洪波,等.一种母乳源鼠李糖乳杆菌及其应用:CN202110486399.9[P].湖南,2022-03-18.
KANG W L, WANG J Q, ZHOU H B, et al.A breast milk-derived Lactobacillus rhamnosus and its application:CN202110486399.9 [P].Hunan, 2022-03-18.
[61] 汪家琦, 顾瑞霞, 潘丽娜, 等.一株短双歧杆菌及其培养方法和用途:CN202110171608.0[P].湖南,2022-07-12.
WANG J Q, GU R X, PAN L N, et al.A strain of Bifidobacterium breve and its culture method and use:CN202110171608.0[P].Hunan, 2022-07-12.
[62] 方曙光, 董瑶, 盖忠辉, 等.一种改善便秘的动物双歧杆菌乳亚种BLa36及其培养方法与应用:CN202210261807.5[P].江苏,2022-05-27.
FANG S G, DONG Y, GAI Z H, et al.Bifidobacterium animalis lactis subspecies lactis BLa36 for improving constipation and its culture method and application:CN202210261807.5[P].Jiangsu, 2022-05-27.
[63] 方曙光, 顾佳悦, 陈婷, 等.一种具有降血糖和降血脂功能的鼠李糖乳酪杆菌LRa66及其应用:CN202310481728.X[P].江苏,2024-06-07.
FANG S G, GU J Y, CHEN T, et al. Lactobacillus rhamnosus LRa66 with hypoglycemic and hypolipidemic functions and its application:CN202310481728.X[P].Jiangsu, 2024-06-07.
[64] 方曙光, 朱明明, 刘欢, 等.乳双歧杆菌BLa80在缓解腹泻和提升肠道免疫能力中的应用:CN202110978637.8[P].江苏,2022-11-22.
FANG S G, ZHU M M, LIU H, et al.Bifidobacterium lactis BLa80 for relieving diarrhea and enhancing intestinal immunity:CN202110978637.8 [P].Jiangsu, 2022-11-22.
[65] 马杰, 张凌宇, 杨慧娟, 等.一株分离自母乳的乳双歧杆菌M8及其应用:CN201910495537.2[P].北京,2021-05-28.
MA J, ZHANG L Y, YANG H J, et al.Bifidobacterium lactis M8 isolated from breast milk and its application:CN201910495537.2 [P].Beijing, 2021-05-28.
[66] 张凌宇, 马晨, 马杰, 等.一株分离自母乳的鼠李糖乳杆菌M9及其应用:CN201910453691.3[P].北京,2021-07-06.
ZHANG L Y, MA C, MA J, et al.Lactobacillus rhamnosus M9 isolated from breast milk and its application:CN201910453691.3[P].Beijing, 2021-07-06.
[67] 孙进, 李双祁, 齐策.一株母乳来源罗伊氏乳杆菌调节母婴免疫功能的应用:CN202010076261.7[P].湖南,2021-06-22.
SUN J, LI S Q, QI C.Application of a Lactobacillus reuteri strain derived from breast milk in regulating maternal-infant immune function:CN202010076261.7[P].Hunan, 2021-06-22.
[68] 姜智姬, 庾炳一, 尹成一, 等.分离自母乳的具有益生菌活性和抑制体重增加活性的乳酸菌:CN200780029113.2[P].韩国,2013-03-13.
JIANG Z J, YU B Y, YIN C Y, et al.Lactic acid bacteria isolated from breast milk with probiotic activity and activity to inhibit weight gain:CN200780029113.2[P].South Korea, 2013-03-13.
[69] 杨善岩, 冯锋将, 李雪龙, 等.可调节肠道菌群的母乳源发酵粘液乳杆菌MSJK0025及其应用:CN202311070808.2[P].浙江,2024-06-11.
YANG S Y, FENG F J, LI X L, et al.Breast milk-derived mucous lactobacillus fermentum MSJK0025 capable of regulating intestinal flora and its application:CN202311070808.2[P].Zhejiang, 2024-06-11.
[70] 房耀维, 刘姝, 杨光, 等.嗜热链球菌FUA329及其发酵生产尿石素A的方法:CN202211224627.6[P].江苏,2024-04-02.
FANG Y W, LIU S, YANG G, et al.Thermophilic Streptococcus FUA329 and its method for fermenting and producing urolithin A:CN202211224627.6[P].Jiangsu, 2024-04-02.
[71] 张艳, 倪永清, 王艺璇, 等.一种母乳源戊糖片球菌及其应用:CN202010812849.4[P].新疆维吾尔自治区,2022-05-20.
ZHANG Y, NI Y Q, WANG Y X, et al.A breast milk-derived Pediococcus pentosaceus and its application:CN202010812849.4 [P].Xinjiang Uygur Autonomous Region, 2022-05-20.
[72] 张婷, 王怡仲, 王续霏, 等.格氏乳杆菌SHMB 0001及其在预防和缓解急性结肠炎中的应用:CN202311109675.5[P].上海,2024-07-30.
ZHANG T, WANG Y Z, WANG X F, et al.Lactobacillus gasseri SHMB 0001 and its application in preventing and alleviating acute colitis:CN202311109675.5 [P].Shanghai, 2024-07-30.
[73] 钟智, 刘文俊, 郭丽如, 等.一株新的链球菌及其制剂在抑制口腔致病菌中的应用:CN202010500826.X[P].内蒙古自治区,2022-02-15.
ZHONG Z, LIU W J, GUO L R, et al.A new strain of Streptococcus and its preparation for inhibiting oral pathogenic bacteria:CN202010500826.X [P].Inner Mongolia Autonomous Region, 2022-02-15.
[74] 国务院办公厅关于印发《专利转化运用专项行动方案(2023—2025年)》的通知[J].中华人民共和国国务院公报, 2023 (31):16-19.
Circular of The General Office of the State Council on issuing and issuing the Special Action Plan for Patent Transformation and Utilization (2023—2025) [J].Bulletin of The State Council of the People’s Republic of China, 2023(31):16-19.
