Effects of Lactiplantibacillus plantarum CN2018 on rats with L-arginine induced gastric motility disorders

  • SUN Xinkai ,
  • MAO Bingyong ,
  • TANG Xin ,
  • ZHANG Qiuxiang ,
  • CUI Shumao ,
  • ZHAO Jianxin
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  • (School of Food Science and Technology, Jiangnan University, Wuxi 214122, China)

Received date: 2024-07-22

  Revised date: 2024-08-29

  Online published: 2025-08-04

Abstract

Lactiplantibacillus plantarum CN2018 is a patented strain capable of resisting infection of Helicobacter pylori, but its effect on gastric motility is still unknown.In this study, we investigated the effect of L.plantarum CN2018 on L-arginine-induced gastric motility disorder in SD rats.The results showed that compared with the model group, L.plantarum CN2018 significantly increased the gastric emptying rate of rats with gastric motility disorders, and showed the trend to increase the volume of gastric juice, the rate of gastric acid excretion and the activity of pepsin, as well as reducing the secretion of gastric acid.Meanwhile, L.plantarum CN2018 significantly increased the transcription levels of tyrosinase receptor gene (c-Kit) and stem cell factor (SCF) in rat gastric antrum tissue.Overall, L.plantarum CN2018 has a good effect in improving gastric motility disorders.

Cite this article

SUN Xinkai , MAO Bingyong , TANG Xin , ZHANG Qiuxiang , CUI Shumao , ZHAO Jianxin . Effects of Lactiplantibacillus plantarum CN2018 on rats with L-arginine induced gastric motility disorders[J]. Food and Fermentation Industries, 2025 , 51(13) : 69 -74 . DOI: 10.13995/j.cnki.11-1802/ts.040535

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