Food and Fermentation Industries >

2025 , Vol. 51 >Issue 18: 338 - 351

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.041965

Simultaneous determination of 32 additive residues and migration in plastic packaging of prefabricated dishes by ultra-performance liquid chromatography-tandem mass spectrometry

  • REN Mengmeng ,
  • XU Dan ,
  • LIU Lulu ,
  • LI Qibin ,
  • YU Wanting ,
  • ZHANG Rujiao ,
  • ZHANG Jingquan ,
  • LI Sha
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  • 1(College of Food Science, Southwest University, Chongqing 400715, China)
    2(Chongqing Institute for Food and Drug Control, Chongqing 401120, China)
    3(Chongqing Dongyin Packaging Co.Ltd., Chongqing 402764, China)
    4(Key Laboratory of Condiment Supervision Technology, State Administration for Market Regulation, Chongqing 401120, China)

Received date: 2024-12-26

  Revised date: 2025-02-15

  Online published: 2025-10-16

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Abstract

In this study, an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed for the determination of 32 additives residues in the plastic packaging of prefabricated dishes, and their migration into food was monitored.For this method, the samples were extracted twice using acetonitrile under ultrasonication for 30 min to determine additive residues, and the aqueous solution of acetonitrile and 0.1% formic acid was used as the mobile phase.Based on the production process of prefabricated dishes, this study simulated the processes of sterilization, storage, and reheating to determine the migration of additives during these processes.Moreover, the residue levels and migration amount of the 32 additives in 100 batches of plastic packaging for prefabricated dishes were determined and compared with the migration amount when they were used as ordinary packaging.The results showed that the 32 additives exhibited a good linear relationship within the range of 5 to 100 ng/mL.The average recoveries ranged from 71.1% to 113.6%, and the relative standard deviations (RSD) were from 0.1% to 8.8%.In the 100 batches of samples, 16% of the samples had excessive residues of antioxidants, while the migration amounts were all within the permissible limits.In addition, the migration after simulating the production process of prefabricated dishes was significantly higher than that of ordinary plastic packaging.In conclusion, the method with simple pretreatment, high sensitivity and wide detection range was developed for the determination of residues and migration of 32 additives in plastic packaging for prefabricated dishes

Key words： plastic packaging of prefabricated dishes; additive; residues; migration; ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)

Cite this article

REN Mengmeng , XU Dan , LIU Lulu , LI Qibin , YU Wanting , ZHANG Rujiao , ZHANG Jingquan , LI Sha . Simultaneous determination of 32 additive residues and migration in plastic packaging of prefabricated dishes by ultra-performance liquid chromatography-tandem mass spectrometry[J]. Food and Fermentation Industries, 2025 , 51(18) : 338 -351 . DOI: 10.13995/j.cnki.11-1802/ts.041965

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