Zanthoxylum bungeanum, a medicinal and edible plants, owes its characteristic numbing sensation to natural unsaturated fatty acid amides, such as the predominant amide hydroxy-α-sanshool.The Zanthoxylum alkylamides has poor chemical stability, thus selecting an appropriate solvent is the key to effective extraction of Zanthoxylum alkylamides and enhancing the chemical stability during storage.Deep eutectic solvents (DES), as a new generation of green solvents, are extensively used for the extraction of natural active substances, but their application in the extraction of Z.bungeanum compounds requires further investigation.This paper prepared seven different DES for extracting alkylamides from Z.bungeanum, and investigated the chemical stability of hydroxy-α-sanshool in different solvents under UV light exposure.Fourier transform infrared spectroscopy was conducted to analyze the protective effect of DES on the chemical stability of hydroxy-α-sanshool.The results showed that the retention time of alkylamides dissolved in DES under UV light was significantly longer than that in methanol.The characteristic absorption peaks of CO and —OH in hydroxy-α-sanshool dissolved in DES exhibited a redshift, broader peaks, and increased intensity compared to undissolved hydroxy-α-sanshool and the DES solvent alone, elucidated its preservation ability is related to the intermolecular hydrogen bond interactions occurring in the solvent.This study can provide theoretical guidance for the development of low-viscosity mature DES solvents tailored to the features of Z.bungeanum, and it also holds significance for the application of DES in the extraction of active compounds from many other plants.
YANG Li
,
WU Qixiao
,
LIU Fuquan
,
XING Yong
,
CHENG Jie
,
ZHAO Zhifeng
. Extraction of alkylamides from Zanthoxylum bungeanum using deep eutectic solvents and the stability of hydroxy-α-sanshool[J]. Food and Fermentation Industries, 2025
, 51(19)
: 192
-198
.
DOI: 10.13995/j.cnki.11-1802/ts.041941
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