Food and Fermentation Industries >

2026 , Vol. 52 >Issue 1: 429 - 440

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.042937

Research progress on the construction and application of biomimetic imprinting sensor for biotoxins

  • WEI Xuebing ,
  • LI Zhaozhou ,
  • TAO Jian ,
  • ZHANG Hongkai ,
  • WAN Ningbo ,
  • YUAN Yunxia ,
  • LI Fang ,
  • CHEN Xiujin ,
  • WANG Yao ,
  • YU Huichun
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  • 1(College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China)
    2(Henan International Joint Laboratory of Food Green Processing and Quality Safety Control, Luoyang 471000, China)
    3(Henan Institute of Food and Salt Industry Inspection Technology, Zhengzhou 450003, China)
    4(Key Laboratory of Rapid Detection and Smart Supervision Technology for Food Safety, State Administration for Market Regulation, Zhengzhou 450003, China)

Received date: 2025-04-06

  Revised date: 2025-06-05

  Online published: 2026-01-22

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Abstract

Biotoxins pose a serious threat to food safety and human health, so the detection of biotoxins in food is particularly essential.Traditional detection methods possess complex sample pretreatments and matrix effects.Molecular imprinting is a biomimetic recognition technique for specific recognition of target molecule in molecular shape.Biomimetic sensors based on molecular imprinting have the advantages of good selectivity and wide adaptability, and have broad application prospects.This review presents the construction methods of biotoxin biomimetic imprinting sensing interfaces, such as bulk polymerization, precipitation polymerization, in-situ polymerization and electrochemical polymerization and so on.The construction of biomimetic imprinting sensing system is also discussed, including the sources of template molecules, the development and screening of new functional monomers, the effects of types and amounts of crosslinking agents on polymer properties and the current status of initiators and porogens.Based on the biomimetic imprinting, the applications of electrochemical, optical and mass sensors are summarized in the detection of phytotoxins, animal toxins, microbial toxins, and marine toxins.The influencing factors of sensitivity and selectivity with different sensors are analyzed.The contents mentioned in this paper provide theoretical basis for the detection of biotoxins in foods and technical supports for food safety supervision.

Key words： biotoxin; biomimetic imprinting; sensor

Cite this article

WEI Xuebing , LI Zhaozhou , TAO Jian , ZHANG Hongkai , WAN Ningbo , YUAN Yunxia , LI Fang , CHEN Xiujin , WANG Yao , YU Huichun . Research progress on the construction and application of biomimetic imprinting sensor for biotoxins[J]. Food and Fermentation Industries, 2026 , 52(1) : 429 -440 . DOI: 10.13995/j.cnki.11-1802/ts.042937

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