Research advances in food polyphenols extraction technology based on deep eutectic solvents

  • YANG Liu ,
  • YU Yanhua ,
  • ZHOU Yujie ,
  • XIE Sida ,
  • ZHAO Ping ,
  • YANG Xiaoqin ,
  • ZOU Lihua
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  • (National-Local Joint Engineering Research Center for High-Efficiency Utilization Technology of Forestry Biomass Resources, College of Material and Chemical Engineering, Southwest Forestry University, Kunming 650224, China)

Received date: 2025-07-27

  Revised date: 2025-10-27

  Online published: 2026-06-24

Abstract

Polyphenols, as important representatives of plant-derived functional ingredients, are widely present in various edible plants.Their unique phenolic hydroxyl structure imparts remarkable antioxidant and antimicrobial activities, making them of great value in the development of functional foods.However, traditional organic solvent extraction methods suffer from low extraction efficiency, residual organic solvents, and environmental hazards, severely limiting their application.In recent years, deep eutectic solvents (DESs), as a new green solvent system, have provided an innovative solution for the efficient and green extraction of food polyphenols due to their low toxicity, biodegradability, high solubility, and designability.This article systematically reviews the structural characteristics and functional activities of food-derived polyphenols, the physicochemical properties, preparation methods, and advantages of food-grade DESs, the research progress in DESs extraction technology, key factors, and the mechanism of action of DESs in polyphenol extraction.Despite significant progress in polyphenol extraction technology based on DESs, challenges remain, including low mass transfer efficiency due to high viscosity of the extraction system, lack of theoretical guidance for system design, difficulty separating polyphenols from solvents, and poor recyclability and reuse.Future efforts should focus on integrating molecular dynamics simulation and machine learning to design low-viscosity, high-solubility, green DESs systems.Furthermore, efficient polyphenol-DESs separation and solvent recycling processes based on membrane separation and ice-salt bath condensation should be developed.These strategies will provide theoretical support for the development of safe and efficient polyphenol extraction processes for functional foods, promoting the green and sustainable development of the food industry.

Cite this article

YANG Liu , YU Yanhua , ZHOU Yujie , XIE Sida , ZHAO Ping , YANG Xiaoqin , ZOU Lihua . Research advances in food polyphenols extraction technology based on deep eutectic solvents[J]. Food and Fermentation Industries, 2026 , 52(11) : 439 -450 . DOI: 10.13995/j.cnki.11-1802/ts.044042

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