A determining method for octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5) and dodecamethylcyclohexasiloxane (D6) in cake trans-migrated from silicone baking mold was established and their safety was evaluated. Under the ultrasonic time of 20 min and repeat extraction for 3 times with acetonitrile, the gas chromatography-mass spectrometry (GC-MS) was performed to detect the contents of D4-D6 in cake baked by silicon rubber mold, and threshold of toxicological concern (TTC) was used to evaluate the safety of D4-D6. The linear range of D4-D6 was 0.12-3.00 μg/mL with the correlation coefficients (R2) greater than 0.996 9. The average recoveries of D4-D6 were 86.10%-104.62% and the relative standard deviation (RSD) were 3.16%-7.53% (n=6). The detection limits were all less than 6.86 ng/mL and quantitative limits less than 23.20 ng/mL. In addition, the total contents of D4-D6 in the cake baked by silicone rubber mold was 8.56 mg/kg. Total estimated daily intake (EDI) of D4-D6, classified as Cramer Ⅲ, was below the TTC threshold (90 μg/d). The method can simply detect the contents of D4-D6 in cake, and the safety issue of D4-D6 in the silicone rubber migrated into the food during processing cannot be ignored.
LIU Yiqi
,
HU Changying
,
SHANG Guiqin
,
ZHANG Hong
,
ZENG Ying
,
ZHU Lei
,
ZHONG Huaining
. Detection method and safety evaluation of three kinds of cyclosiloxanes in cake trans-migrated from silicone rubber mold[J]. Food and Fermentation Industries, 2019
, 45(18)
: 228
-233
.
DOI: 10.13995/j.cnki.11-1802/ts.021013
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