Preparation of Ganoderma lucidum spore oligosaccharide and itsregulation on gut microbiota

  • YANG Kai ,
  • ZHANG Yajie ,
  • ZHANG Su ,
  • CAI Ming ,
  • PI Xionge ,
  • HU Junrong ,
  • GUAN Rongfa ,
  • SUN Peilong
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  • 1(College of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310014, China)
    2(Ningbo Huikang Life Science and Technology Co. Ltd, Fenghua 315500, China)
    3(Institute of Plant Protection and Microbiology, Zhejiang Academy of Agricultural Science, Hangzhou 310021, China)
    4(R & D Center, Hangzhou Wahaha Science and Technology Co. Ltd, Hangzhou 310018, China)

Received date: 2020-01-03

  Online published: 2020-06-11

Abstract

Unbroken/broken Ganoderma lucidum spore oligosaccharides (UGLS-O, BGLS-O) were extracted from sporoderm-unbroken and sporoderm-broken spores of Ganoderma lucidum, respectively. The effects of GLS oligosaccharides on gut microbiota were examined by using an in vitro fermentation model. The changes of short-chain fatty acids (SCFAs) and gas production in metabolites, the utilization of oligosaccharides, and the changes of bacterial phase were determined. The results showed that both UGLS-O and BGLS-O could be effectively utilized by gut microbiota. Compared with a blank control group, the groups added with GLS oligosaccharides significantly increased the yields of main SCFAs (e.g., acetic acid, propionic acid, butyric acid), and produced a small amount of gas to promote intestinal peristalsis. Furthermore, the relative abundances of beneficial bacteria (e.g., Bifidobacterium and Lactobacillus) were increased, while Escherichia coli was decreased. In conclusion, the prepared GLS oligosaccharides possessed significant effects on probiotic regulation of gut microbiota.

Cite this article

YANG Kai , ZHANG Yajie , ZHANG Su , CAI Ming , PI Xionge , HU Junrong , GUAN Rongfa , SUN Peilong . Preparation of Ganoderma lucidum spore oligosaccharide and itsregulation on gut microbiota[J]. Food and Fermentation Industries, 2020 , 46(9) : 37 -42 . DOI: 10.13995/j.cnki.11-1802/ts.023251

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