Food and Fermentation Industries >

2020 , Vol. 46 >Issue 17: 277 - 284

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.024121

Research advances of oligonucleotide aptamer-based biosensor for foodborne pathogen detection

  • ZENG Huijun ,
  • FU Shihui ,
  • YAN Tao ,
  • YANG Xiaoping ,
  • LIU Ping ,
  • XU Wei ,
  • DONG Qiuhua ,
  • LI Juan
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  • Wuhan Institute for Food and Cosmetic Control,Wuhan 430012,China

Received date: 2020-04-07

  Revised date: 2020-04-24

  Online published: 2020-10-14

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Abstract

Aptamers are single-stranded DNA or RNA molecules, which can specifically recognize and bind to their targets. Due to its simplicity of synthesis, simplicity of modification, strong specificity, high stability and wide range of various target molecules, it had been applied in many fields such as food safety, disease diagnosis and public health. This article reviewed the development in the field of aptamer-based biosensor for foodborne pathogen detection, focused on the classification of aptamer screening technologies and nine aptamer-based biosensors application technologies, including colorimetric aptasensors, fluorescence aptasensors, chemiluminescence aptasensors, surface-enhanced Raman scattering aptasensors, surface plasmon resonance aptasensors, flow cytometry aptasensors, lateral flow aptasensors, electrochemical aptasensors and quartz crystal microbalance aptasensors. Although significant progress has been achieved in the field in the last decade, challenges or drawbacks in the applications still remain to be overcame. Lastly, the new trends about aptamer-based biosensors for the foodborne pathogen were also discussed.

Key words： aptamer; biosensor; foodborne pathogen

Cite this article

ZENG Huijun , FU Shihui , YAN Tao , YANG Xiaoping , LIU Ping , XU Wei , DONG Qiuhua , LI Juan . Research advances of oligonucleotide aptamer-based biosensor for foodborne pathogen detection[J]. Food and Fermentation Industries, 2020 , 46(17) : 277 -284 . DOI: 10.13995/j.cnki.11-1802/ts.024121

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