In order to get the best carrier,we used different materials to immobilize the salt-tolerant yeast.The optimal immobilization parameters were studied by orthogonal experiments,and range analysis and variance analysis were done by using SPSS.The final result showed the sodium alginate and calcium chloride were better than agar and gelatin in immobilization of the salt-resistance yeast.The optimum conditions were the concentration of sodium alginate 4 g/100 mL,calcium chloride 1.4 mol/L,at 28℃.Under this condition,the effect of immobilization was better.