Rice wine is regarded as the national banquet wine and is widely known for its health benefit.This ar-ticle mainly reviewed the nutritional value of rice wine and the material bases of uncomfortable reactions(such as "Headache & Dizziness"and"Excessive Internal Heat") after drinking rice wine.The main factors that cause "Headache & Dizziness"were alcohol,fusel oil,aldehydes and so on;the contents and radios of nutrients in the wine were the principal causes that tended to set off "Excessive Internal Heat"reaction.The paper concluded with the proposal of a preliminary solution based on material ground.