Effects of different concentrations of L-cys,citric acid,ascorbic acid,calcium and chloride on inhibiting browning degree of fresh-cut pears were investigated.Based on the single-factor test,four-factor three-level orthogonal experiment was conducted to optimize the formula which could replace sodium bisulfite.The optimum combination treatment was 1% calcium chlorid + 0.5% ascorbic acid +0.5% L-Cys.Comparative tests showed that the optimal formula is better than sodium bisulfit in the areas of inhibiting browning,MDA content and keep the Vc content.