Food and Fermentation Industries >

2010 , Vol. 36 >Issue 12: 105 - 110

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.2010.12.005

Food and Fermentation Industries

Optimization of Fermentation Conditions in Production of ACE Inhibitory Peptides From Cotton Seed Protein

  • Chang Tong ,
  • Cao Yu-sheng ,
  • Li Hai-xing ,
  • Chen Yan
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Online published: 2010-12-25

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Abstract

Angiotensin-I-converting enzyme(ACE) inhibitory peptide was derived from cotton seed protein fermented with Bacillus subtilis NCT314.The fermentation conditions including temperature,time,pH and inoculum size were investigated.Based on the single factor experiments,the fermentation condition was optimized by response surface methodology.The result showed the optimum fermentation condition was temperature 32.08℃,time 22.6 h and pH 7.2.Under this condition,the ACE inhibitory ratio of fermented liquid reached to 78.06 %,and IC50 value was 6.67 mg/ml.

Key words： cotton seed protein; fermentation; ACE inhibitory peptides; response surface methodology

Cite this article

Chang Tong , Cao Yu-sheng , Li Hai-xing , Chen Yan . Optimization of Fermentation Conditions in Production of ACE Inhibitory Peptides From Cotton Seed Protein[J]. Food and Fermentation Industries, 2010 , 36(12) : 105 -110 . DOI: 10.13995/j.cnki.11-1802/ts.2010.12.005

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