Effect of different factors on the extraction of Toona sinensis with surfactant and microwave was studied.The optimum condition was obtained by orthogonal experiment.The results showed that the best condition was: water extraction,0.8% mass ratio Coconut Diethanol Amide in the pretreatment solution(material to solvent ratio 1∶20,boiling 10min under 90℃),microwave power 180W,extraction for 10min,5 times.